Gálvez-Ruiz Alberto, Schatz Patrik
Neuro-ophthalmology Division (AG-R), King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; Retina Division (PS), King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; and Department of Ophthalmology (PS), Clinical Sciences, Scane County University Hospital, University of Lund, Lund, Sweden.
J Neuroophthalmol. 2016 Jun;36(2):131-3. doi: 10.1097/WNO.0000000000000329.
Vascular risk factors are increasing rapidly in the Middle East. Growing inactivity and obesity have contributed to an epidemic of Type 2 diabetes mellitus (DM) in the Arab population. Microvascular palsies of the third, fourth, and sixth cranial nerves, which occur in an isolated manner, are relatively common in patients with DM, hypertension, or other vascular risk factors.
In this retrospective analysis, patients with diabetes with microvascular palsies were assessed for the prevalence of diabetic retinopathy (DR). We compared these data with the prevalence of DR in the general population of diabetics in Saudi Arabia and to a similar published study done in an American population.
In total, 126 patients with diabetes were included in the study. The sixth nerve was most frequently involved in 67 patients (53%). Seventy-seven patients (61%) had DR, compared with 49 (39%) without DR. The prevalence of DR in the general population of Saudi patients with diabetes ranged from 30% to 36.1%.
Our study demonstrated a higher prevalence of DR in patients with microvascular palsies compared with the general population of patients with diabetes in the Arab population. This is in contrast to a previous study in an American population. Our results might be secondary to differences between the 2 populations, in particular, the continued increase in the prevalence of vascular risk factors (mainly diabetes) and poor control of these risk factors in the Middle East.
中东地区血管危险因素迅速增加。日益缺乏运动和肥胖导致阿拉伯人群中2型糖尿病(DM)流行。孤立出现的第三、第四和第六颅神经微血管麻痹在糖尿病、高血压或其他血管危险因素患者中相对常见。
在这项回顾性分析中,对患有微血管麻痹的糖尿病患者进行糖尿病视网膜病变(DR)患病率评估。我们将这些数据与沙特阿拉伯糖尿病普通人群中DR的患病率以及在美国人群中进行的一项类似已发表研究进行比较。
该研究共纳入126例糖尿病患者。第六神经受累最为常见,共67例(53%)。77例(61%)有DR,无DR的有49例(39%)。沙特糖尿病患者普通人群中DR的患病率在30%至36.1%之间。
我们的研究表明,与阿拉伯人群中糖尿病普通患者相比,微血管麻痹患者中DR的患病率更高。这与之前在美国人群中的一项研究结果相反。我们的结果可能归因于这两个人群之间的差异,特别是中东地区血管危险因素(主要是糖尿病)患病率持续上升以及这些危险因素控制不佳。