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沙特阿拉伯南部失明和糖尿病视网膜病变的患病率及病因

Prevalence and causes of blindness and diabetic retinopathy in Southern Saudi Arabia.

作者信息

Hajar Saad, Al Hazmi Ali, Wasli Mustafa, Mousa Ahmed, Rabiu Mansour

机构信息

Department of Ophthalmology, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia. Tel. +966 (11) 2889999 Ext. 1024. E-mail.

出版信息

Saudi Med J. 2015 Apr;36(4):449-55. doi: 10.15537/smj.2015.4.10371.

Abstract

OBJECTIVES

To determine the prevalence and causes of blindness and diabetic retinopathy (DR) in Jazan district, Southern Saudi Arabia.

METHODS

Using the standardized Rapid Assessment for Avoidable Blindness (RAAB) and DR cross-sectional methodology, 3800 subjects were randomly selected from the population of ≥50 years of age in Jazan, Saudi Arabia between November 2011 and January 2012. Participants underwent screening comprised of interview, random blood glucose test, and ophthalmic assessment including visual acuity (VA) and fundus examination. Among participants with VA less than 6/18 in either eye, the cause(s) of visual impairment was determined. Participants were classified as diabetic if they had previous diagnoses of diabetes, or random blood glucose more than 200 mg/dl. Diabetic participants were assessed for DR using dilated fundus examination. All data were recorded using the RAAB + DR standardized forms.

RESULTS

The prevalence of bilateral blindness less than 3/60 was 3.3% (95% confidence interval [CI]: 2.74 - 3.90). Cataract was the leading cause of blindness (58.6%); followed by posterior segment diseases (20%), which included DR (7; 3.3%). The prevalence of diabetes mellitus (DM) was 22.4%, (95% CI: 21.09 - 23.79]), among them; 27.8% had DR. The prevalence of sight-threatening DR was 5.7%.

CONCLUSION

The prevalence of DM and the corresponding proportion of DR in this region is lower than that reported in other regions of Saudi Arabia. However, the prevalence of blindness not related to DR is relatively higher than the other studies.

摘要

目的

确定沙特阿拉伯南部吉赞地区失明和糖尿病视网膜病变(DR)的患病率及病因。

方法

采用标准化的可避免失明快速评估(RAAB)和DR横断面研究方法,于2011年11月至2012年1月期间,从沙特阿拉伯吉赞地区50岁及以上人群中随机选取3800名受试者。参与者接受了包括访谈、随机血糖检测以及眼科评估(包括视力[VA]和眼底检查)在内的筛查。在任何一只眼睛视力低于6/18的参与者中,确定视力损害的原因。如果参与者既往诊断为糖尿病或随机血糖超过200mg/dl,则被分类为糖尿病患者。对糖尿病参与者使用散瞳眼底检查评估DR。所有数据均使用RAAB + DR标准化表格记录。

结果

双眼视力低于3/60的失明患病率为3.3%(95%置信区间[CI]:2.74 - 3.90)。白内障是失明的主要原因(58.6%);其次是眼后段疾病(20%),其中包括DR(7例;3.3%)。糖尿病(DM)的患病率为22.4%(95%CI:21.09 - 23.79),其中27.8%患有DR。威胁视力的DR患病率为5.7%。

结论

该地区DM的患病率及相应的DR比例低于沙特阿拉伯其他地区报道的水平。然而,与DR无关的失明患病率相对高于其他研究。

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