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[致命性肺栓塞的发病率,特别提及基础疾病及天气的影响]

[The incidence of fatal lung emboli with special reference to the underlying disease and the effect of weather].

作者信息

Putzke H P, Möbius C, Günther U, Bargenda M, Dobberphul J

机构信息

Institut für Pathologische Anatomie, Wilhelm-Pieck-Universität Rostock.

出版信息

Z Gesamte Inn Med. 1989 Feb 15;44(4):106-10.

PMID:2718529
Abstract

The frequency of the fatal pulmonary embolism in the autopsy material of Rostock University undergoes greater variations. After an increase of the incidence in connection with hyperalimentation and increase of age to the twofold to threefold between 1922 and 1974 as possible sequel of a prophylaxis of thrombosis a decrease of maximally 12.4 to 8.2% is to be established. The average age is 67.8 years, females are more affected to the relation of 1:1.6. Clinically the diagnosis of causes of death was exactly made in 25.9%. In the relation of causes dominate basic diseases of the cardiovascular and respiratory system with disturbances of the haemodynamics, malignant tumours without significant preference of certain organ carcinomas and infectious-toxic complications. A conspicuous accumulation concerned the chronic respiratory syndrome, often a polypathia existed. In the region of the coast of the Baltic Sea pulmonary embolisms appeared statistically significantly more frequently in fine weather phases and at beginning fine weather, respectively, with indifferent or tendencially rising global radiation on the day of the event and particularly in winter season. An influence of passages of weather fronts could not be established.

摘要

罗斯托克大学尸检材料中致命性肺栓塞的发生率变化较大。在1922年至1974年间,与高营养及年龄增长相关的发病率有所上升,作为血栓形成预防措施的可能后果,发病率增长了两倍至三倍,之后最大降幅达12.4%至8.2%。平均年龄为67.8岁,女性受影响的比例与男性之比为1:1.6。临床上,确切死因诊断的比例为25.9%。在死因方面,心血管和呼吸系统的基础疾病伴血流动力学紊乱、恶性肿瘤(无特定器官癌的明显偏好)以及感染性中毒并发症占主导。一个显著的聚集现象与慢性呼吸综合征有关,通常存在多种疾病并存的情况。在波罗的海沿岸地区,肺栓塞在天气晴朗阶段以及开始晴朗天气时出现的统计频率明显更高,事件发生当天的全球辐射无变化或呈趋势性上升,尤其是在冬季。未发现天气锋面过境的影响。

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