Kalra Sanjay, Gupta Yashdeep, Unnikrishnan Ambika Gopalakrishnan
Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
Department of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Endocrinol Metab. 2016 May-Jun;20(3):408-11. doi: 10.4103/2230-8210.180003.
This communication explores the concept of flexibility, a propos insulin preparations and insulin regimes used in the management of type 2 diabetes. The flexibility of an insulin regime or preparation is defined as their ability to be injected at variable times, with variable injection-meal time gaps, in a dose frequency and quantum determined by shared decision making, with a minimal requirement of glucose monitoring and health professional consultation, with no compromise on safety, efficiency and tolerability. The relative flexibility of various basal, prandial and dual action insulins, as well as intensive regimes, is compared. The biopsychosocial model of health is used to assess the utility of different insulins while encouraging a philosophy of flexible insulin usage.
本通讯探讨了灵活性的概念，涉及用于2型糖尿病管理的胰岛素制剂和胰岛素治疗方案。胰岛素治疗方案或制剂的灵活性定义为它们能够在可变时间注射，注射与进餐时间间隔可变，剂量频率和剂量由共同决策确定，对血糖监测和医疗专业人员咨询的要求最低，同时在安全性、有效性和耐受性方面不妥协。比较了各种基础胰岛素、餐时胰岛素和双相胰岛素以及强化治疗方案的相对灵活性。健康的生物心理社会模型用于评估不同胰岛素的效用，同时鼓励灵活使用胰岛素的理念。
