Swetha Rayapadi G, Ramaiah Sudha, Anbarasu Anand, Sekar Kanagaraj
Medical & Biological Computing Laboratory, School of Biosciences and Technology, VIT University, Vellore 632 014, India.
Laboratory for Structural Biology and Bio-Computing, Department of Computational and Data Sciences, Indian Institute of Science, Bangalore 560 012, India.
Adv Bioinformatics. 2016;2016:1673284. doi: 10.1155/2016/1673284. Epub 2016 Apr 14.
Ebola Virus Disease (EVD) is a life-threatening haemorrhagic fever in humans. Even though there are many reports on EVD, the protein precursor functions and virulent factors of ebolaviruses remain poorly understood. Comparative analyses of Ebolavirus genomes will help in the identification of these important features. This prompted us to develop the Ebolavirus Database (EDB) and we have provided links to various tools that will aid researchers to locate important regions in both the genomes and proteomes of Ebolavirus. The genomic analyses of ebolaviruses will provide important clues for locating the essential and core functional genes. The aim of EDB is to act as an integrated resource for ebolaviruses and we strongly believe that the database will be a useful tool for clinicians, microbiologists, health care workers, and bioscience researchers.
埃博拉病毒病(EVD)是一种威胁人类生命的出血热。尽管有许多关于埃博拉病毒病的报道,但埃博拉病毒的蛋白质前体功能和致病因素仍知之甚少。对埃博拉病毒基因组进行比较分析将有助于识别这些重要特征。这促使我们开发了埃博拉病毒数据库(EDB),并且我们提供了各种工具的链接,这些工具将帮助研究人员在埃博拉病毒的基因组和蛋白质组中定位重要区域。对埃博拉病毒的基因组分析将为定位必需和核心功能基因提供重要线索。EDB的目的是作为埃博拉病毒的综合资源,我们坚信该数据库将成为临床医生、微生物学家、医护人员和生物科学研究人员的有用工具。