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儿童眶周蜂窝织炎:静脉抗生素治疗结果分析

Periorbital cellulitis in children: Analysis of outcome of intravenous antibiotic therapy.

作者信息

Gonçalves Rita, Menezes Carlos, Machado Rute, Ribeiro Isabel, Lemos José A

机构信息

a Department of Ophthalmology , Pedro Hispano Hospital , Matosinhos , Portugal.

b Department of Pediatrics , Pedro Hispano Hospital , Matosinhos , Portugal.

出版信息

Orbit. 2016 Aug;35(4):175-80. doi: 10.1080/01676830.2016.1176205. Epub 2016 May 18.

Abstract

Periorbital cellulitis is a relatively common ocular disease in the pediatric population. Early diagnosis of this disease with a prompt intervention is critical to avoid vision and life-threatening complications. In the last years, medical therapy has been expanding for the treatment of orbital cellulitis, instead of the standard surgical approach. The purpose of this study was to describe the outcome of treatment with intravenous antibiotic of periorbital cellulitis in children. A retrospective review of all children admitted with periorbital cellulitis in our hospital between January 2002 and July 2013 was conducted. Cases were divided in two subgroups, pre-septal and post-septal infection. The demographics, clinical findings, treatment and outcomes were analyzed. In total 110 children were included, 93 with pre-septal and 17 with post-septal cellulitis. The mean age was 3.5 years in children with pre-septal cellulitis and 5.5 years in those with post-septal cellulitis (p = 0.149). For both subgroups the most common predisposing factor was sinusitis. Intravenous antibiotic therapy was successful in all except one patient with an orbital abscess who required surgical intervention. In our study complete recovery was achieve in all (except for one) children with periorbital cellulitis treated with intravenous antibiotics only.

摘要

眶周蜂窝织炎是儿科人群中一种相对常见的眼部疾病。早期诊断并及时干预对于避免视力损害和危及生命的并发症至关重要。在过去几年中,眶蜂窝织炎的治疗已从标准的手术方法转向药物治疗。本研究的目的是描述儿童眶周蜂窝织炎静脉使用抗生素治疗的结果。对2002年1月至2013年7月间我院收治的所有眶周蜂窝织炎患儿进行回顾性研究。病例分为两个亚组,即眶隔前感染和眶隔后感染。分析了人口统计学、临床表现、治疗方法及结果。共纳入110例患儿,其中眶隔前蜂窝织炎93例,眶隔后蜂窝织炎17例。眶隔前蜂窝织炎患儿的平均年龄为3.5岁,眶隔后蜂窝织炎患儿为5.5岁(p = 0.149)。两个亚组中最常见的诱发因素均为鼻窦炎。除1例眼眶脓肿患者需要手术干预外,静脉使用抗生素治疗均成功。在我们的研究中,所有(除1例)仅接受静脉抗生素治疗的眶周蜂窝织炎患儿均实现了完全康复。

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