Okay Berker, Kalinbacoglu Ceren Dogan, Akkoc Gulsen, Hatipoglu Halil Ugur, Dogan Omer, Sahin Kamil, Buyukkayhan Derya
Department of Pediatrics, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkiye.
Department of Pediatric Infectious Diseases, Marmara University Pendik Training and Research Hospital, Istanbul, Turkiye.
North Clin Istanb. 2025 Jan 8;12(1):89-94. doi: 10.14744/nci.2023.58630. eCollection 2025.
Preseptal cellulitis is an infection of the palpebrae and the periorbital superficial tissue and is more common in children than adults. This study aims to evaluate the demographic and clinical characteristics of children hospitalized for preseptal cellulitis and the factors affecting these characteristics.
In this retrospective, single-center study, 101 children hospitalized for preseptal cellulitis between March 2019 and March 2022 were included. The patients were divided into 2 groups as under five years old and over five years old.
56 patients (55.4%) were male and the median age was 56 (24-89) months. All patients had eye swelling. Periorbital erythema was seen in 81 (80.1%), conjunctivitis in 39 (38.6%), eye discharge in 30 (29.7%) patients. The most common treatment was ampicillin-sulbactam+clindamycin (77.2%). Mean treatment duration was 8.42±2.89 days, clinical improvement was 5.01±2.20 days. Patients with leukocytosis had longer duration of treatment compared to patients without leukocytosis (9.3±3.1 vs. 7.8±2.5 days, p=0.009). While the lymphocyte level was higher in patients under 5 years of age compared to patients over 5 years of age (p<0.001); neutrophil (p<0.001), hemoglobin (p=0.002) and NLR (p<0.001) levels were low. The duration of clinical improvement was short in patients under 5 years of age (4.4±1.6 vs. 5.6±2.5 days, p=0.005).
The most common finding in patients with preseptal cellulitis was swelling in the eye. The presence of leukocytosis in patients may be used to predict the duration of treatment. Age was an important factor in predicting the duration of clinical improvement in patients.
眶隔前蜂窝织炎是睑部和眶周浅表组织的感染，在儿童中比成人更常见。本研究旨在评估因眶隔前蜂窝织炎住院的儿童的人口统计学和临床特征以及影响这些特征的因素。
在这项回顾性单中心研究中，纳入了2019年3月至2022年3月期间因眶隔前蜂窝织炎住院的101名儿童。患者被分为5岁以下和5岁以上两组。
56例患者（55.4%）为男性，中位年龄为56（24 - 89）个月。所有患者均有眼部肿胀。81例（80.1%）出现眶周红斑，39例（38.6%）出现结膜炎，30例（29.7%）患者有眼部分泌物。最常用的治疗方法是氨苄西林 - 舒巴坦 + 克林霉素（77.2%）。平均治疗 duration为8.42±2.89天，临床改善时间为5.01±2.20天。与无白细胞增多的患者相比，白细胞增多的患者治疗时间更长（9.3±3.1天对7.8±2.5天，p = 0.009）。5岁以下患者的淋巴细胞水平高于5岁以上患者（p < 0.001）；中性粒细胞（p < 0.001）、血红蛋白（p = 0.002）和NLR（p < 0.001）水平较低。5岁以下患者的临床改善时间较短（4.4±1.6天对5.6±2.5天，p = 0.005）。
眶隔前蜂窝织炎患者最常见的表现是眼部肿胀。患者白细胞增多的情况可用于预测治疗 duration。年龄是预测患者临床改善 duration的重要因素。
