基于寿命可调晶格应变量子点的活细胞多寿命编码。
Living Cell Multilifetime Encoding Based on Lifetime-Tunable Lattice-Strained Quantum Dots.
机构信息
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology. Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences , Shenzhen 518055, P. R. China.
出版信息
ACS Appl Mater Interfaces. 2016 Jun 1;8(21):13187-91. doi: 10.1021/acsami.6b03795. Epub 2016 May 19.
A series of functional quantum dots (QDs) with widely tunable near-infrared fluorescence emission (620-750 nm) and lifetime (30-160 ns) were synthesized via lattice strain and showed excellent photo, colloid, pH, and lifetime stabilities. The well-defined targeting QDs were first developed for a living cell multilifetime encoding strategy to track and recognize specified tumor cell clusters dependent on lifetime distribution using fluorescence lifetime imaging microscopy.
通过晶格应变合成了一系列具有可调谐近红外荧光发射（620-750nm）和寿命（30-160ns）的功能量子点（QDs），并表现出优异的光稳定性、胶体稳定性、pH 值稳定性和寿命稳定性。这些具有明确靶向性的量子点首先被开发出来，用于一种活细胞多寿命编码策略，该策略使用荧光寿命成像显微镜依赖寿命分布来跟踪和识别特定的肿瘤细胞簇。
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