Franco Joanna Pimenta de Araujo, Serra Márcio Soares, Lima Ricardo Barbosa, D'Acri Antônio Macedo, Martins Carlos José
Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
An Bras Dermatol. 2016 Apr;91(2):209-11. doi: 10.1590/abd1806-4841.20163867.
The scleroderma en coup de sabre is a variant of localized scleroderma that occurs preferentially in children. The disease progresses with a proliferative and inflammatory phase and later atrophy and residual deformity, which are treated with surgical techniques such as injectable fillers, transplanted or autologous fat grafting and resection of the lesion. Among the most widely used fillers is hyaluronic acid. However, there are limitations that motivate the search for alternatives, such as polymethylmethacrylate, a permanent filler that is biocompatible, non-toxic, non-mutagenic and immunologically inert. In order to illustrate its application, a case of scleroderma en coup de sabre in a 17-year-old patient, who was treated with polymethylmethacrylate with excellent aesthetic results, is reported.
剑伤性硬皮病是局限性硬皮病的一种变体，多见于儿童。该病经历增殖性和炎症期，随后出现萎缩和残留畸形，可通过注射填充剂、移植或自体脂肪移植以及病变切除等手术技术进行治疗。透明质酸是最广泛使用的填充剂之一。然而，这些填充剂存在局限性，促使人们寻找替代品，比如聚甲基丙烯酸甲酯，一种永久性填充剂，具有生物相容性、无毒、无致突变性且免疫惰性。为说明其应用，本文报道了一例17岁剑伤性硬皮病患者，使用聚甲基丙烯酸甲酯治疗后取得了极佳的美学效果。
