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孤立性丛状神经纤维瘤酷似血管病变。

Isolated plexiform neurofibroma mimicking a vascular lesion.

作者信息

Stefano Paola Cecilia, Apa Sebastian Nicolas, Lanoël Agustina Maria, María Josefina Sala, Sierre Sergio, Pierini Adrián Martin

机构信息

National Hospital of Pediatrics "Prof. Dr. Juan P. Garrahan", Buenos Aires, Argentina.

出版信息

An Bras Dermatol. 2016 Apr;91(2):240-2. doi: 10.1590/abd1806-4841.20164300.

DOI:10.1590/abd1806-4841.20164300
PMID:27192529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4861577/
Abstract

Plexiform neurofibromas are benign tumors originating from peripheral nerve sheaths, generally associated with Neurofibromatosis Type 1 (NF1). They are diffuse, painful and sometimes locally invasive, generating cosmetic problems. This report discusses an adolescent patient who presented with an isolated, giant plexiform neurofibroma on her leg that was confused with a vascular lesion due to its clinical aspects. Once the diagnosis was confirmed by surgical biopsy, excision of the lesion was performed with improvement of the symptoms.

摘要

丛状神经纤维瘤是起源于周围神经鞘的良性肿瘤,通常与1型神经纤维瘤病(NF1)相关。它们呈弥漫性,有疼痛感,有时具有局部侵袭性,会产生美容问题。本报告讨论了一名青少年患者,她腿部出现了一个孤立的巨大丛状神经纤维瘤,因其临床表现被误诊为血管病变。经手术活检确诊后,切除了病变,症状得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/f6551dfd08e5/abd-91-02-0240-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/8bb5c809a70e/abd-91-02-0240-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/0dd5478f1a57/abd-91-02-0240-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/805971d132b4/abd-91-02-0240-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/367431e362a7/abd-91-02-0240-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/f6551dfd08e5/abd-91-02-0240-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/8bb5c809a70e/abd-91-02-0240-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/0dd5478f1a57/abd-91-02-0240-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/805971d132b4/abd-91-02-0240-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/367431e362a7/abd-91-02-0240-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/4861577/f6551dfd08e5/abd-91-02-0240-g05.jpg

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本文引用的文献

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Ann Chir Plast Esthet. 2013 Dec;58(6):694-9. doi: 10.1016/j.anplas.2011.08.006. Epub 2011 Sep 13.
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甲床孤立性神经纤维瘤:一例报告及文献复习
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一例累及腓总神经所有分支的孤立性巨大丛状神经纤维瘤。
Arch Orthop Trauma Surg. 2007 Oct;127(8):709-12. doi: 10.1007/s00402-007-0303-1. Epub 2007 Mar 22.
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Sporadic and multiple neurofibromas in the head and neck region: a retrospective study of 33 years.头颈部散发性和多发性神经纤维瘤:一项33年的回顾性研究
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