Department of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Department of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Immunity. 2016 May 17;44(5):1079-81. doi: 10.1016/j.immuni.2016.04.025.
Although regulatory T cells protect people from autoimmunity, two recent papers in Immunity (Malchow et al., 2016; Kieback et al., 2016) demonstrate that these cells are also a crisis averted. Without the proper education in the thymus, these cells will turn on their host and cause autoimmunity.
尽管调节性 T 细胞能保护人体免受自身免疫的影响,但最近在《免疫》(Immunity)杂志上发表的两篇论文(Malchow 等人,2016;Kieback 等人,2016)表明,这些细胞也是避免危机的关键。如果在胸腺中没有得到适当的教育,这些细胞就会转而攻击宿主并引发自身免疫。