Chen Jie, Chen Shenjie, Mao Wei
Department of Cardiology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Cardiology. 2016;135(1):43-7. doi: 10.1159/000445938. Epub 2016 May 19.
Most cases of acute hydrogen sulfide (H2S) poisoning in China are caused by sewage processing. With the rapid development of urbanization in China, H2S poisoning is showing an increasing trend. Here, we report a case of survival from severe H2S poisoning. A 40-year-old worker was found in the underground sewer lines. He was unresponsive with bilaterally dilated pupils and had poor oxygen saturation. After intubation, he was transferred to the intensive care unit. He developed respiratory failure, acute myocardial infarction, ventricular arrhythmia and left ventricular function impairment, requiring artificial ventilation with highly concentrated oxygen, hyperbaric oxygen treatment and drug therapy. Consequently, he completely recovered from the respiratory and cardiac failure. Cases of survival after severe H2S intoxication have been rarely reported. Such exposures may bring about severe myocardial impairment, which is most likely to benefit from angiotensin-converting enzyme inhibition and β-blocker.
中国大多数急性硫化氢(H₂S)中毒病例是由污水处理引起的。随着中国城市化的快速发展,H₂S中毒呈上升趋势。在此,我们报告一例重度H₂S中毒后存活的病例。一名40岁的工人被发现在地下污水管道中。他无反应,双侧瞳孔散大,血氧饱和度低。插管后,他被转入重症监护病房。他出现了呼吸衰竭、急性心肌梗死、室性心律失常和左心室功能损害,需要高浓度氧气人工通气、高压氧治疗和药物治疗。结果,他完全从呼吸和心力衰竭中康复。重度H₂S中毒后存活的病例鲜有报道。此类接触可能导致严重的心肌损害,而这最有可能从血管紧张素转换酶抑制和β受体阻滞剂治疗中获益。