Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea2Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Division of Statistics, Medical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
JAMA Ophthalmol. 2016 Jul 1;134(7):778-84. doi: 10.1001/jamaophthalmol.2016.1158.
Visual impairment (VI) is an emerging public health concern, especially considering the aging population. However, unlike other major chronic diseases, VI is often overlooked by investigators assessing the burden of diseases.
To provide a description of preference weights for VI and chronic diseases from a national survey and estimate the corresponding burden of these diseases.
DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional study was conducted using a multistage, probability-cluster survey, which can produce nationally representative estimates. Data on 29 639 participants 19 years or older from the 2008-2012 Korean National Health and Nutrition Examination Survey were analyzed in terms of vision assessment, status of chronic diseases, and the European Quality of Life-Five Dimensions Questionnaire (EQ-5D). Visual impairment was defined as the presenting distance best-corrected visual acuity of worse than decimal 0.5. Data analysis was conducted from August 14, 2008, and September 7, 2015.
Preference weights (utilities) and prevalence-based quality-adjusted life-year (QALY) losses.
Of the 29 639 participants, 28 382 with VA or EQ-5D measurements were included in the analysis; they had a mean (SE) age of 45.05 (0.19) years and a mean EQ-5D index of 0.948 (0.001). The preference weight for VI was -0.0549 (95% CI, -0.0777 to -0.0321), which was the third highest value among the 12 diseases analyzed-preceded only by the preference weights for osteoarthritis or rheumatoid arthritis (-0.0688; 95% CI, -0.748 to -0.0628) and stroke (-0.0666; 95% CI, -0.0854 to -0.0479). The estimated annual QALY loss from VI was -74.93 years per 100 000 person-years; this loss is comparable to or higher than that associated with other major chronic conditions (eg, diabetes mellitus, dyslipidemia, stroke, myocardial infarction/ischemic heart disease, asthma, obesity, and anemia). Visual impairment accounted for 4.77% of the total estimated QALY loss in the Korean population aged 19 years or older.
The present study provides a description of preference weights for VI and various chronic diseases from a national survey. Furthermore, it reveals the distributions of public burden from these conditions, and compared them in this regard. Although details might vary across the populations having different cultural and socioeconomic backgrounds, the results underscore the importance of VI for quality of life and as a public health burden compared with other major chronic diseases.
视力障碍(VI)是一个新出现的公共卫生问题,尤其是考虑到人口老龄化。然而,与其他主要慢性病不同,在评估疾病负担的研究中,VI 经常被忽视。
提供全国性调查中 VI 和慢性病偏好权重的描述,并估计这些疾病的相应负担。
设计、地点和参与者:这是一项横断面研究,使用多阶段、概率聚类调查,可产生全国代表性估计。对 2008-2012 年韩国国家健康和营养检查调查中 29639 名 19 岁或以上参与者的视力评估、慢性病状况和欧洲生活质量-五个维度问卷(EQ-5D)数据进行了分析。视力障碍定义为最佳矫正视力的表现距离差于十进制 0.5。数据分析于 2008 年 8 月 14 日至 2015 年 9 月 7 日进行。
偏好权重(效用)和基于患病率的质量调整生命年(QALY)损失。
在 29639 名参与者中,有 28382 名有 VA 或 EQ-5D 测量值,纳入分析;他们的平均(SE)年龄为 45.05(0.19)岁,平均 EQ-5D 指数为 0.948(0.001)。VI 的偏好权重为-0.0549(95%CI,-0.0777 至-0.0321),在分析的 12 种疾病中位列第三-仅低于骨关节炎或类风湿关节炎(-0.0688;95%CI,-0.748 至-0.0628)和中风(-0.0666;95%CI,-0.0854 至-0.0479)。VI 每年导致的估计 QALY 损失为每 10 万人年 74.93 年;这一损失与其他主要慢性疾病(如糖尿病、血脂异常、中风、心肌梗死/缺血性心脏病、哮喘、肥胖和贫血)相当或更高。VI 占韩国 19 岁及以上人群总估计 QALY 损失的 4.77%。
本研究从全国性调查中提供了 VI 和各种慢性病的偏好权重描述。此外,它揭示了这些疾病的公共负担分布,并在这方面进行了比较。尽管在具有不同文化和社会经济背景的人群中可能存在细节差异,但结果强调了 VI 对生活质量的重要性以及与其他主要慢性疾病相比对公共卫生的负担。