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用于中心性浆液性脉络膜视网膜病变的低强度/高密度阈下二极管微脉冲激光

LOW-INTENSITY/HIGH-DENSITY SUBTHRESHOLD DIODE MICROPULSE LASER FOR CENTRAL SEROUS CHORIORETINOPATHY.

作者信息

Luttrull Jeffrey K

机构信息

Private Practice, Ventura, California.

出版信息

Retina. 2016 Sep;36(9):1658-63. doi: 10.1097/IAE.0000000000001005.

Abstract

PURPOSE

To review the results of low-intensity/high-density subthreshold micropulse laser (SDM) for treatment of central serous chorioretinopathy.

METHOD

The records of all patients treated in a retinal subspecialty practice with SDM for central serous chorioretinopathy were reviewed.

RESULTS

Eleven consecutive eyes of 11 patients treated between October 2011 and April 2014 were identified for study, 9 men and 2 women, aged 30 to 55 (mean = 46). Symptom duration before treatment ranged 1 month to 7 months (mean = 3.6 months) and after treatment with SDM laser, follow-up ranged 1 month to 45 months (mean = 14). Preoperative visual acuities ranged 20/20 to 20/100 (mean = 20/37) and postoperative visual acuities were 20/15 to 20/40 (mean = 20/24) (P = 0.01, paired t-test). Maximum retinal thickness ranged 314 μm to 893 μm (mean = 508) preoperatively and 222 μm to 365 μm (mean = 250) postoperatively for an average 258 μm reduction in retinal thickness (P = 0.002, paired t-test). Subretinal fluid was eliminated in all eyes by 3 months after treatment (mean = 1.3 months). The number of SDM laser spot applications ranged 295 to 1431 per treatment session (mean = 772). One eye required retreatment, but for a new leakage locus 4 months after initial treatment. There were no adverse treatment effects.

CONCLUSION

An SDM laser seems to be safe and effective for the treatment of central serous chorioretinopathy. As advocated in the literature, a higher treatment density and larger treatment area, as reported in this article, may improve clinical results.

摘要

目的

回顾低强度/高密度阈下微脉冲激光(SDM)治疗中心性浆液性脉络膜视网膜病变的结果。

方法

回顾在视网膜专科诊所接受SDM治疗中心性浆液性脉络膜视网膜病变的所有患者的记录。

结果

确定了2011年10月至2014年4月期间接受治疗的11例患者的11只连续眼睛进行研究,其中男性9例,女性2例,年龄30至55岁(平均46岁)。治疗前症状持续时间为1个月至7个月(平均3.6个月),SDM激光治疗后随访时间为1个月至45个月(平均14个月)。术前视力范围为20/20至20/100(平均20/37),术后视力为20/15至20/40(平均20/24)(配对t检验,P = 0.01)。术前视网膜最大厚度范围为314μm至893μm(平均508μm),术后为222μm至365μm(平均250μm),视网膜厚度平均减少258μm(配对t检验,P = 0.002)。治疗后3个月内所有眼睛的视网膜下液均消失(平均1.3个月)。每次治疗的SDM激光光斑应用次数范围为295至1431次(平均772次)。一只眼睛需要再次治疗,但为初始治疗后4个月出现的新渗漏部位。未出现不良治疗效果。

结论

SDM激光治疗中心性浆液性脉络膜视网膜病变似乎安全有效。如本文所报道,正如文献中所提倡的,更高的治疗密度和更大的治疗面积可能会改善临床结果。

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