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[儿童哮喘中的胃食管反流]

[Gastroesophageal reflux in childhood asthma].

作者信息

Petrů V, Snajdauf J, Honzová S, Vondrácková L, Kabelka M

出版信息

Cesk Pediatr. 1989 Jan;44(1):11-4.

PMID:2720809
Abstract

Gastrooesophageal reflux (GER) may participate in the development and persistence of asthmatic complaints. For its detection various examination methods may be used such as oesophagography, oesophageal manometry and pH-metry, ultrasonography, isotope scintigraphy, oesophagoscopy. By means of these methods we detected GER in 27 children, i. e. 41% of a total number of 65 asthmatic children with a medium severe and severe form of the disease. Because of failure of conservative treatment of reflux and hitherto used anti-asthmatic therapy, in 1984 to 1986 in 11 children surgical treatment of reflux by Nissen's fundoplication was indicated. The group comprised 9 boys and 2 girls aged 2 to 14 years. The effect of the operation was evaluated after an interval of 1.5 to 3.5 years following operation. Surgical treatment was successful in four patients (36%) and partly successful in 5 patients (45%). Despite these encouraging results the indication surgery in GER in asthmatic patients still is strictly individual.

摘要

胃食管反流(GER)可能参与哮喘症状的发生和持续。为检测GER,可采用多种检查方法,如食管造影、食管测压和pH测定、超声检查、同位素闪烁扫描、食管镜检查。通过这些方法,我们在27名儿童中检测到了GER,即在65名中重度和重度哮喘患儿总数中占41%。由于反流的保守治疗及以往使用的抗哮喘治疗均无效,1984年至1986年,对11名儿童进行了尼森胃底折叠术治疗反流。该组包括9名男孩和2名女孩,年龄在2至14岁之间。术后1.5至3.5年对手术效果进行评估。手术治疗4例成功(占比36%),5例部分成功(占比45%)。尽管有这些令人鼓舞的结果,但哮喘患者GER手术的指征仍需严格个体化。

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