Petrů V, Snajdauf J, Honzová S, Vondrácková L, Kabelka M
Cesk Pediatr. 1989 Jan;44(1):11-4.
Gastrooesophageal reflux (GER) may participate in the development and persistence of asthmatic complaints. For its detection various examination methods may be used such as oesophagography, oesophageal manometry and pH-metry, ultrasonography, isotope scintigraphy, oesophagoscopy. By means of these methods we detected GER in 27 children, i. e. 41% of a total number of 65 asthmatic children with a medium severe and severe form of the disease. Because of failure of conservative treatment of reflux and hitherto used anti-asthmatic therapy, in 1984 to 1986 in 11 children surgical treatment of reflux by Nissen's fundoplication was indicated. The group comprised 9 boys and 2 girls aged 2 to 14 years. The effect of the operation was evaluated after an interval of 1.5 to 3.5 years following operation. Surgical treatment was successful in four patients (36%) and partly successful in 5 patients (45%). Despite these encouraging results the indication surgery in GER in asthmatic patients still is strictly individual.
胃食管反流(GER)可能参与哮喘症状的发生和持续。为检测GER,可采用多种检查方法,如食管造影、食管测压和pH测定、超声检查、同位素闪烁扫描、食管镜检查。通过这些方法,我们在27名儿童中检测到了GER,即在65名中重度和重度哮喘患儿总数中占41%。由于反流的保守治疗及以往使用的抗哮喘治疗均无效,1984年至1986年,对11名儿童进行了尼森胃底折叠术治疗反流。该组包括9名男孩和2名女孩,年龄在2至14岁之间。术后1.5至3.5年对手术效果进行评估。手术治疗4例成功(占比36%),5例部分成功(占比45%)。尽管有这些令人鼓舞的结果,但哮喘患者GER手术的指征仍需严格个体化。