慢性疼痛可以预防吗？

Can Chronic Pain Be Prevented?

作者信息

Badiola Ignacio J

机构信息

Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Penn Pain Medicine Center, 1840 South Street, Philadelphia, PA 19146, USA.

出版信息

Anesthesiol Clin. 2016 Jun;34(2):303-15. doi: 10.1016/j.anclin.2016.01.008.

DOI:10.1016/j.anclin.2016.01.008

PMID:27208712

Abstract

All chronic pain begins at some discrete point in time. Significant strides in the understanding of mechanisms and risk factors associated with the transition from a new, or acute, pain experience to a chronic pain condition have been made over the past 20 years. These insights provide the hope of one day being able to modify or even halt this pathophysiologic progression. This article reviews some of the current knowledge of this transition as well as the evidence currently available to best prevent and treat it using persistent surgical pain as a model.

摘要

所有慢性疼痛都始于某个特定的时间点。在过去20年里，我们对与从新的（即急性）疼痛体验转变为慢性疼痛状况相关的机制和风险因素的理解取得了重大进展。这些见解让我们有望有朝一日能够改变甚至阻止这种病理生理进展。本文以持续性手术疼痛为模型，回顾了有关这种转变的一些当前知识以及目前可用于最佳预防和治疗的证据。