Saint Louis University School of Medicine.
Saint Louis University School of Medicine.
J Pain. 2018 Dec;19(12):1367-1383. doi: 10.1016/j.jpain.2018.06.002. Epub 2018 Jun 30.
Persistent Post-Mastectomy Pain (PPMP) is a common condition that can follow surgeries for breast cancer, the most common cancer in women. Because of the frequency of PPMP and its potential severity, it has received increasing research attention. This manuscript reviews the recent research literature, beginning with a brief history and then relevant medical, surgical, demographic, and psychosocial risk factors. Subsequently, social, psychological, and functional sequelae that have been linked to PPMPS are considered, as is research on current pharmacological, psychological, and rehabilitative approaches to treatment. The review concludes with a discussion of directions for future research and treatment that might reduce the incidence and impact of PPMP on breast cancer survivors. PERSPECTIVE: This article describes current research literature involving mechanisms, risks, and treatments related to persistent post-mastectomy pain. Implications of research findings also are discussed for pre- and post-surgical approaches to pain management, current treatments, and promising research directions.
乳房切除术后持续性疼痛（PPMP）是一种常见的病症，可能发生在乳腺癌手术后，乳腺癌是女性最常见的癌症。由于 PPMP 的频率及其潜在的严重程度，它受到了越来越多的研究关注。本文综述了最近的研究文献，首先简要回顾了历史，然后介绍了相关的医学、手术、人口统计学和社会心理风险因素。随后，考虑了与 PPMPS 相关的社会、心理和功能后遗症，以及目前针对治疗的药理学、心理学和康复方法的研究。本文最后讨论了未来研究和治疗的方向，这些研究和治疗可能会降低 PPMP 对乳腺癌幸存者的发生率和影响。观点：本文描述了与持续性乳房切除术后疼痛相关的机制、风险和治疗的当前研究文献。还讨论了研究结果对疼痛管理的术前和术后方法、当前治疗方法以及有前途的研究方向的影响。
