Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Departments of Neurology Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Eur Radiol. 2017 Feb;27(2):447-453. doi: 10.1007/s00330-016-4406-3. Epub 2016 May 21.
To evaluate the usefulness of 3D nerve-sheath signal increased with inked rest-tissue rapid acquisition of relaxation enhancement imaging (SHINKEI) in patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
This institutional review board-approved retrospective study included 14 CIDP patients and nine normal subjects. The signal-to-noise ratio (SNR), contrast ratio (CR), and the size of the cervical ganglions and roots were measured by two raters.
The SNRs of the ganglions and roots were larger in patients with CIDP (9.55 ± 3.87 and 9.81 ± 3.64) than in normal subjects (7.21 ± 2.42 and 5.70 ± 2.14, P < 0.0001, respectively). The CRs of the ganglions and roots were larger in patients with CIDP (0.77 ± 0.08 and 0.68 ± 0.12) than in normal subjects (0.72 ± 0.07 and 0.53 ± 0.11, P < 0.0001, respectively). The sizes of the ganglions and the roots were larger in patients with CIDP (6.44 ± 1.61 mm and 4.89 ± 1.94 mm) than in normal subjects (5.24 ± 1.02 mm and 3.39 ± 0.80 mm, P < 0.0001, respectively).
Patients with CIDP could be distinguished from controls on 3D SHINKEI.
• 3D SHINKEI could visualize brachial plexus with high spatial resolution. • CIDP patients showed increased SNR, CR, and the size of brachial plexus. • 3D SHINKEI could discriminate CIDP patients from normal subjects.
评估 3D 神经鞘信号增加与墨渍静息组织快速弛豫增强成像（SHINKEI）在慢性炎症性脱髓鞘性多发性神经病（CIDP）患者中的应用价值。
本回顾性研究经机构审查委员会批准，纳入 14 例 CIDP 患者和 9 例正常对照。由 2 名评估者测量神经节和神经根的信噪比（SNR）、对比比（CR）和大小。
CIDP 患者的神经节和神经根 SNR 较大（分别为 9.55±3.87 和 9.81±3.64），明显高于正常对照组（分别为 7.21±2.42 和 5.70±2.14，P均<0.0001）。CIDP 患者的神经节和神经根 CR 较大（分别为 0.77±0.08 和 0.68±0.12），明显高于正常对照组（分别为 0.72±0.07 和 0.53±0.11，P均<0.0001）。CIDP 患者的神经节和神经根大小较大（分别为 6.44±1.61 mm 和 4.89±1.94 mm），明显大于正常对照组（分别为 5.24±1.02 mm 和 3.39±0.80 mm，P均<0.0001）。
3D SHINKEI 可区分 CIDP 患者与对照组。
• 3D SHINKEI 可高空间分辨率显示臂丛。• CIDP 患者的 SNR、CR 和臂丛大小增加。• 3D SHINKEI 可区分 CIDP 患者与正常对照。
