Frings C S, Battaglia D J, White R M
Chris Frings & Associates, Birmingham, AL 35226.
Clin Chem. 1989 May;35(5):891-4.
We report results of a blind study designed to determine the accuracy of drugs-of-abuse testing in urine as done in 31 laboratories across the United States. The drugs studied were amphetamines, cannabinoids, cocaine, opiates, and phencyclidine. These laboratories confirmed all positive drug results with a different analytical method. Ten urine samples were sent to each laboratory, which resulted in 1486 trials. There were no false-positive results. The overall accuracy rate was 97%. Our study demonstrates that urine drug testing can be accurate when performed by qualified staff, using up-to-date screening and confirmation methods, appropriate quality-assurance measures, and a chain of custody.
我们报告了一项盲法研究的结果，该研究旨在确定美国31个实验室进行的尿液药物滥用检测的准确性。所研究的药物有苯丙胺、大麻素、可卡因、阿片类药物和苯环己哌啶。这些实验室用不同的分析方法对所有阳性药物检测结果进行了确认。向每个实验室送去了10份尿液样本，共进行了1486次检测。没有出现假阳性结果。总体准确率为97%。我们的研究表明，当由合格人员进行尿液药物检测时，使用最新的筛查和确认方法、适当的质量保证措施以及监管链，检测结果可以是准确的。
