Instituto de Investigaciones Marinas y Costeras (IIMyC), Universidad Nacional de Mar del Plata (UNMDP), Toxicología Ambiental, Dpto. Ciencias Marinas, FCEyN, Funes 3350, 7600 Mar del Plata, Argentina.
Instituto de Investigaciones Marinas y Costeras (IIMyC), Universidad Nacional de Mar del Plata (UNMDP), Toxicología Ambiental, Dpto. Ciencias Marinas, FCEyN, Funes 3350, 7600 Mar del Plata, Argentina.
Mar Pollut Bull. 2016 Aug 15;109(1):650-654. doi: 10.1016/j.marpolbul.2016.05.012. Epub 2016 May 19.
The concentrations of mercury (Hg), selenium (Se) and metallothioneins (MT) were evaluated in fetuses, calves, juveniles and adults of the endangered coastal Franciscana dolphin (Pontoporia blainvillei) from Argentina. Mercury concentrations varied among analyzed tissues (liver, kidney, muscle and brain), with liver showing the higher concentrations in all specimens. An age-dependent accumulation was found in liver, kidney and brain. No significant relationship between Hg and MT concentrations was found for all tissues analyzed. Hepatic Hg molar concentrations were positively correlated with those of Se, indicating a great affinity between these two elements. Furthermore, dark granules of HgSe were observed in Kupffer cells in the liver by electron microscopy, suggesting the role of this macrophage in the detoxification of Hg. A transfer of Hg through placenta was proved. The presence of Hg in brain in all age classes did not show concentrations associated with neurotoxicity.
评估了来自阿根廷濒危沿海麦哲伦海豚（Pontoporia blainvillei）的胎儿、小牛、幼体和成体的汞（Hg）、硒（Se）和金属硫蛋白（MT）浓度。Hg 浓度在分析的组织（肝、肾、肌肉和脑）中有所不同，所有标本的肝脏中均显示出较高的浓度。在肝、肾和脑中有年龄依赖性的积累。在分析的所有组织中，均未发现 Hg 和 MT 浓度之间存在显著关系。肝组织中 Hg 的摩尔浓度与 Se 的摩尔浓度呈正相关，表明这两种元素之间具有很强的亲和力。此外，电镜下观察到肝库普弗细胞中存在 HgSe 暗颗粒，表明这种巨噬细胞在 Hg 的解毒中发挥作用。通过胎盘转移 Hg 被证明。所有年龄段的大脑中都存在 Hg，但并未显示出与神经毒性相关的浓度。
