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开放式与微创式成人输尿管再植术:国家外科质量改进计划(NSQIP)数据库中的30天结果分析

Open Vs Minimally Invasive Adult Ureteral Reimplantation: Analysis of 30-day Outcomes in the National Surgical Quality Improvement Program (NSQIP) Database.

作者信息

Packiam Vignesh T, Cohen Andrew J, Nottingham Charles U, Pariser Joseph J, Faris Sarah F, Bales Gregory T

机构信息

Section of Urology, University of Chicago, Chicago, IL.

Section of Urology, University of Chicago, Chicago, IL.

出版信息

Urology. 2016 Aug;94:123-8. doi: 10.1016/j.urology.2016.05.025. Epub 2016 May 19.

Abstract

OBJECTIVE

To examine 30-day outcomes of robotic-assisted and pure laparoscopic ureteral reimplantation (LUR) vs open ureteral reimplantation (OUR) in adult patients for benign disease.

METHODS

We identified adult patients undergoing LUR or OUR by urologists between 2006 and 2013 using the American College of Surgeons National Surgical Quality Improvement Program database, excluding those with concomitant partial cystectomy or ureterectomy. Multivariable regression modeling was used to assess for the independent association of minimally invasive surgery (MIS) with 30-day complications, reoperations, or readmissions.

RESULTS

Of 512 patients identified, 300 underwent LUR and 212 underwent OUR. Baseline characteristics including age, race, body mass index, and cardiovascular comorbidities were similar between LUR and OUR (all P > .05). Patients who underwent LUR had higher median preoperative serum creatinine (1.1 mg/dL vs 1.0 mg/dL, P = .03), increased presence of a resident (51% vs 34%, P < .01), and shorter hospitalization (1 [interquartile range 0-3] days vs 4 [interquartile range 3-6] days, P < .01) compared to patients who underwent OUR. LUR had lower overall complications (9% vs 28%, P < .01), especially with regard to transfusions (1% vs 11%, P < .01), superficial wound infections (0% vs 5%, P < .01), and urinary tract infections (5% vs 11%, P = .03). On multiple regression analyses, MIS was an independent predictor of lower overall complication rate (odds ratio [OR] 0.24 [0.14-0.40], P < .01), but was not predictive of readmission (OR 0.93 [0.44-1.98], P = .16) or reoperation (OR 2.09 [0.90-4.82], P = .10).

CONCLUSION

In the largest current series assessing the impact of MIS on adult ureteral reimplantation, data from the National Surgical Quality Improvement Program demonstrate that LUR results in decreased 30-day complications.

摘要

目的

研究成年良性疾病患者行机器人辅助与单纯腹腔镜输尿管再植术(LUR)及开放输尿管再植术(OUR)后的30天结局。

方法

我们利用美国外科医师学会国家外科质量改进计划数据库,确定了2006年至2013年间由泌尿科医生实施LUR或OUR的成年患者,排除同时行部分膀胱切除术或输尿管切除术的患者。采用多变量回归模型评估微创手术(MIS)与30天并发症、再次手术或再次入院之间的独立关联。

结果

在确定的512例患者中,300例行LUR,212例行OUR。LUR组和OUR组的基线特征,包括年龄、种族、体重指数和心血管合并症相似(均P>0.05)。与行OUR的患者相比,行LUR的患者术前血清肌酐中位数更高(1.1mg/dL对1.0mg/dL,P = 0.03),住院医师参与比例更高(51%对34%,P<0.01),住院时间更短(1天[四分位间距0 - 3]对4天[四分位间距3 - 6],P<0.01)。LUR的总体并发症发生率更低(9%对28%,P<0.01),尤其是在输血方面(1%对11%,P<0.01)、浅表伤口感染方面(0%对5%,P<0.01)以及尿路感染方面(5%对11%,P = 0.03)。在多因素回归分析中,MIS是总体并发症发生率较低的独立预测因素(比值比[OR]0.24[0.14 - 0.40],P<0.01),但不是再次入院(OR 0.93[0.44 - 1.98],P = 0.16)或再次手术(OR 2.09[0.90 - 4.82],P = 0.10)的预测因素。

结论

在目前评估MIS对成年输尿管再植术影响的最大系列研究中,国家外科质量改进计划的数据表明,LUR可降低30天并发症发生率。

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