Mehendale Sanjay, Kumar C P Girish, Venkatasubramanian S, Prasanna T
National Institute of Epidemiology, Indian Council of Medical Research, II Main Road, TNHB, Ayapakkam, Chennai, 600077, India.
Indian J Pediatr. 2016 Oct;83(10):1087-92. doi: 10.1007/s12098-016-2152-9. Epub 2016 May 23.
To enumerate the cases of intussusception in Chennai during 2012-2013, describe the clinical profile, outcomes of case management and highlight the importance of systematically collecting this data in lieu of rotavirus vaccine introduction in India.
Medical records of pediatric intussusception cases admitted in eight large hospitals in Chennai from July 2012 through June 2013 were retrospectively reviewed. Demographic and clinical data including diagnostic and treatment practices were obtained. Cases were categorized based on the diagnostic certainty criteria stipulated by the Brighton collaboration on intussusception.
During the one year of study period, 205 cases of intussusception were diagnosed in 8 hospitals in Chennai city of India. The median age at presentation was 9 mo (Inter Quartile Range, IQR 6-14) with a male to female ratio of 1.8:1. The commonest site of intussusception was ileocolic (80.4 %). Most of the cases (59.8 %) were managed non-surgically. Direct surgical intervention was carried out in 26.5 % cases whereas in 11.8% of cases, surgery was required after failure of non-surgical measures. Median duration of hospital stay was 3 d (IQR 1-5).
This study documents the case burden of intussusception among children in Chennai in a calendar year. Data on receipt of rotavirus vaccine was not available. The authors recommend collection of rotavirus vaccine data among all cases of intussusception in the country, and do retrospective analysis in other parts of the country and prospective surveillance in pediatric / immunization clinics to assess impact of rotavirus vaccine on intussusception rates in the post rotavirus vaccine introduction scenario.
统计钦奈2012 - 2013年肠套叠病例数，描述其临床特征、病例管理结果，并强调在印度引入轮状病毒疫苗的情况下系统收集此类数据的重要性。
回顾性分析2012年7月至2013年6月钦奈8家大型医院收治的小儿肠套叠病例的病历。获取人口统计学和临床数据，包括诊断和治疗方法。根据布莱顿肠套叠协作组规定的诊断确定性标准对病例进行分类。
在为期一年的研究期间，印度钦奈市的8家医院共诊断出205例肠套叠病例。发病时的中位年龄为9个月（四分位间距，IQR 6 - 14），男女比例为1.8:1。肠套叠最常见的部位是回结肠（80.4%）。大多数病例（59.8%）采用非手术治疗。26.5%的病例进行了直接手术干预，而11.8%的病例在非手术措施失败后需要手术。中位住院时间为3天（IQR 1 - 5）。
本研究记录了钦奈一年内儿童肠套叠的病例负担。关于轮状病毒疫苗接种的数据不可用。作者建议收集该国所有肠套叠病例的轮状病毒疫苗数据，并在该国其他地区进行回顾性分析，在儿科/免疫诊所进行前瞻性监测，以评估在引入轮状病毒疫苗后该疫苗对肠套叠发病率的影响。
