aDepartment of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba City, Japan bCritical Care Medicine, Institute for Nutrition Research, Rabin Medical Center, Beilison Hospital, Petah Tikva, Israel cNutrition Unit, Geneva University Hospital, Geneva, Switzerland.
Curr Opin Crit Care. 2016 Aug;22(4):292-8. doi: 10.1097/MCC.0000000000000313.
The review focuses on the use of parenteral nutrition and enteral nutrition in critically ill patients to optimize the nutrition care throughout the ICU stay. The key message is: you have the choice!
Enteral nutrition has been recommended for critically ill patients, whereas parenteral nutrition has been considered harmful and to be avoided. However, recent studies have challenged this theory. They demonstrated that enteral nutrition is frequently associated with energy and protein undernutrition, whereas parenteral nutrition becomes deleterious only if overfeeding is induced. Measuring energy expenditure by indirect calorimetry, in most cases, enables accurate determination of the energy needs to optimize the prescription of nutrition. Protein targets should also be considered for adequate feeding. Parenteral nutrition can be used as a supplement or as an alternative to enteral nutrition in case of gastrointestinal intolerance, to enable adequate energy, and protein provision.
Parenteral nutrition is a powerful tool to optimize nutrition care of critically ill patients to improve clinical outcome, if prescribed according to the individual needs of the patients. After 3-4 days of attempt to feed enterally, enteral nutrition or parenteral nutrition can be used alternatively or combined, as long as the target is reached with special attention to avoid hypercaloric feeding.
本综述重点关注危重症患者肠外营养和肠内营养的应用,以优化 ICU 期间的营养护理。关键信息是:你有选择!
肠内营养已被推荐用于危重症患者,而肠外营养则被认为是有害的,应避免使用。然而,最近的研究对这一理论提出了挑战。他们表明,肠内营养常常与能量和蛋白质摄入不足有关,而只有在过度喂养时,肠外营养才会产生不良影响。通过间接量热法测量能量消耗,在大多数情况下,可以准确确定能量需求,以优化营养处方。还应考虑蛋白质目标,以提供充足的喂养。如果出现胃肠道不耐受,肠外营养可以作为肠内营养的补充或替代,以提供足够的能量和蛋白质。
如果根据患者的个体需求进行个体化处方,肠外营养是优化危重症患者营养护理以改善临床结局的有力工具。在尝试经肠内喂养 3-4 天后,可以替代或联合使用肠内营养或肠外营养,只要达到目标,并特别注意避免过度喂养。