Shin Jin Yong, Yi Hyung Suk
Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University, Jeonju, Republic of Korea.
Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine, Busan, Republic of Korea.
Burns. 2016 Nov;42(7):1369-1376. doi: 10.1016/j.burns.2016.03.012. Epub 2016 May 20.
Accurate assessment of burn depth is important for determination of treatment modality. Laser Doppler imaging (LDI) is known to be an objective and effective measurement tool in burn depth assessment. Our study evaluated the diagnostic accuracy of LDI across enrolled studies and subgroups.
A systematic literature review and meta-analysis were performed using MEDLINE, EMBASE, and Cochrane databases. Data from LDI cases were extracted from all primary studies and categorized into four cell values (true positives, false positives, true negatives, and false negatives). Subgroup analyses were performed according to perfusion units of LDI, clinical criteria of superficial and deep burns during the treatment period, and publication date of enrolled studies.
The search strategy identified 321 publications. After screening, 10 articles were selected for review. The pooled sensitivity and specificity of LDI in all enrolled studies and subgroups were found to be similarly high. However, the sensitivity of LDI in our meta-analysis was not as high as that identified in previous studies.
Although LDI in burn depth assessment was identified as an accurate measurement tool in this meta-analysis, careful clinical assessment should be performed along with LDI in patients with deep burns.
准确评估烧伤深度对于确定治疗方式至关重要。激光多普勒成像（LDI）是烧伤深度评估中一种客观有效的测量工具。我们的研究评估了LDI在纳入研究及亚组中的诊断准确性。
使用MEDLINE、EMBASE和Cochrane数据库进行系统的文献综述和荟萃分析。从所有原始研究中提取LDI病例的数据，并分类为四个细胞值（真阳性、假阳性、真阴性和假阴性）。根据LDI的灌注单位、治疗期间浅度和深度烧伤的临床标准以及纳入研究的发表日期进行亚组分析。
检索策略共识别出321篇出版物。筛选后，选择了10篇文章进行综述。发现LDI在所有纳入研究和亚组中的合并敏感性和特异性同样很高。然而，我们荟萃分析中LDI的敏感性不如先前研究中确定的高。
尽管在这项荟萃分析中LDI被确定为烧伤深度评估中的一种准确测量工具，但对于深度烧伤患者，应在LDI的同时进行仔细的临床评估。
