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食管癌切除术后胃出口梗阻:术后内镜下幽门扩张术有效性和安全性的回顾性分析

Gastric Outlet Obstruction After Esophagectomy: Retrospective Analysis of the Effectiveness and Safety of Postoperative Endoscopic Pyloric Dilatation.

作者信息

Maus Martin K H, Leers Jessica, Herbold Till, Bludau Marc, Chon Seung-Hun, Kleinert Robert, Hescheler Daniel A, Bollschweiler Elfriede, Hölscher Arnulf H, Schäfer Hartmut, Alakus Hakan

机构信息

Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.

出版信息

World J Surg. 2016 Oct;40(10):2405-11. doi: 10.1007/s00268-016-3575-1.

Abstract

BACKGROUND AND AIMS

Delayed gastric emptying after esophagectomy with gastric replacement can pose a significant postoperative problem, often leading to aspiration and pneumonia. The present study analyzes retrospectively the effectiveness of endoscopic pyloric dilatation for post-surgical gastric outlet obstruction.

METHODS

Between March 2006 and March 2010, 403 patients underwent a transthoracic en-bloc esophagectomy and reconstruction with a gastric tube and intrathoracic esophagogastrostomy. In patients with postoperative symptoms of an outlet dysfunction and the confirmation by endoscopy, pyloric dilatations were performed without preference with either 20- or 30-mm balloons.

RESULTS

A total of 89 balloon dilatations of the pylorus after esophagectomy were performed in 60 (15.6 %) patients. In 21 (35 %) patients, a second dilatation of the pylorus was performed. 55 (61.8 %) dilatations were performed with a 30-mm balloon and 34 (38.2 %) with a 20-mm balloon. The total redilatation rate for the 30-mm balloon was 20 % (n = 11) and 52.9 % (n = 18) for the 20-mm balloon (p < 0.001). All dilatations were performed without any complications.

CONCLUSIONS

Pylorus spasm contributes to delayed gastric emptying leading to postoperative complications after esophagectomy. Endoscopic pyloric dilatation after esophagectomy is a safe procedure for treatment of gastric outlet obstruction. The use of a 30-mm balloon has the same safety profile but a 2.5 lower redilatation rate compared to the 20-mm balloon. Thus, the use of 20-mm balloons has been abandoned in our clinic.

摘要

背景与目的

食管切除胃代食管术后胃排空延迟是一个严重的术后问题,常导致误吸和肺炎。本研究回顾性分析内镜下幽门扩张术治疗术后胃出口梗阻的有效性。

方法

2006年3月至2010年3月,403例患者接受了经胸整块食管切除、胃管重建及胸内食管胃吻合术。对于有术后出口功能障碍症状且经内镜证实的患者,使用20mm或30mm球囊进行幽门扩张术,无偏好选择。

结果

60例(15.6%)患者共进行了89次食管切除术后幽门球囊扩张术。21例(35%)患者进行了第二次幽门扩张术。55次(61.8%)扩张使用30mm球囊,34次(38.2%)使用20mm球囊。30mm球囊的再扩张率为20%(n = 11),20mm球囊为52.9%(n = 18)(p < 0.001)。所有扩张均无并发症发生。

结论

幽门痉挛导致胃排空延迟,进而引起食管切除术后的并发症。食管切除术后内镜下幽门扩张术是治疗胃出口梗阻的安全方法。使用30mm球囊与20mm球囊安全性相同,但再扩张率低2.5倍。因此,我们诊所已不再使用20mm球囊。

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