Lobanok L M, Kirienkov A E
Fiziol Zh (1978). 1989 Mar-Apr;35(2):65-9.
Hypoxia is shown to decrease chronotropic and inotropic responses of the isolated heart of mature rats to stimulation of M-choline receptors. In aged tissue hypoxia has no influence on the inotropic response to carbocholine effect. The results permit a conclusion to be made on the higher resistance of cholinergic mechanisms that regulate the cardiac function to hypoxic effects in aged animals.
研究表明，缺氧会降低成年大鼠离体心脏对M胆碱受体刺激的变时性和变力性反应。在老年组织中，缺氧对卡巴胆碱作用的变力性反应没有影响。这些结果使得我们可以得出结论，即调节心脏功能的胆碱能机制在老年动物中对缺氧作用具有更高的抗性。
