膀胱癌根治性膀胱切除术后盆腔复发的计数：一项加拿大多机构研究。
Enumerating pelvic recurrence following radical cystectomy for bladder cancer: A Canadian multi-institutional study.
作者信息
Eapen Libni J, Jones Edward, Kassouf Wassim, Lambert Carole, Morgan Scott C, Moussa Madeleine, Nam Robert, Parliament Matthew, Russell Laurie, Saad Fred, Siemens D Robert, Souhami Luis, Szumacher Ewa, Tyldesley Scott, Xu Yan, Zbieranowski Ingrid, Breau Rodney H, Belanger Eric, Black Peter, Estey Eric, Bowan Julie, Bora Bishwajit, Brundage Michael, Chung Peter, Fleshner Neil, Evans Andrew, Bauman Glenn, Izawa Jonathan, Davidson Chris, Brimo Fadi
机构信息
The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, Canada;
BC Cancer Agency, BC, Canada;
出版信息
Can Urol Assoc J. 2016 Mar-Apr;10(3-4):90-4. doi: 10.5489/cuaj.3456.
INTRODUCTION
We aimed to enumerate the rate of pelvic recurrence following radical cystectomy at university-affiliated hospitals in Canada.
METHODS
Canadian, university-affiliated hospitals were invited to participate. They were asked to identify the first 10 consecutive patients undergoing radical cystectomy starting January 1, 2005, who had urothelial carcinoma stages pT3/T4 N0-2 M0. The first 10 consecutive cases starting January 1, 2005 who met these criteria were the patients submitted by that institution with information regarding tumour stage, age, number of nodes removed, and last known clinical status in regard to recurrence and patterns of failure.
RESULTS
Of the 111 patients, 80% had pT3 and 20% pT4 disease, with 62% being node-negative, 14% pN1, and 27% pN2; 57% had 10 or more nodes removed. Cumulative incidence of pelvic relapse was 40% among the entire group.
CONCLUSIONS
This review demonstrates a high rate of pelvic tumour recurrence following radical cystectomy for pT3/T4 urothelial cancer.
引言
我们旨在统计加拿大大学附属医院根治性膀胱切除术后盆腔复发率。
方法
邀请加拿大大学附属医院参与。要求他们找出2005年1月1日起连续接受根治性膀胱切除术的前10例患有pT3/T4 N0 - 2 M0期尿路上皮癌的患者。2005年1月1日起符合这些标准的连续前10例病例即为该机构提交的患者，包含肿瘤分期、年龄、切除淋巴结数量以及关于复发和失败模式的最后已知临床状态等信息。
结果
111例患者中，80%患有pT3期疾病，20%患有pT4期疾病，62%淋巴结阴性，14%为pN1，27%为pN2；57%切除了10个或更多淋巴结。整个组中盆腔复发的累积发生率为40%。
结论
本综述表明，对于pT3/T4期尿路上皮癌，根治性膀胱切除术后盆腔肿瘤复发率较高。
Zotero 插件