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重力辅助引流成像在小儿肾积水评估中的应用

Gravity-assisted drainage imaging in the assessment of pediatric hydronephrosis.

作者信息

Acker Matthew R, Clark Roderick, Anderson Peter

机构信息

Department of Urology, University of Miami, Miami, FL, U.S.;

Division of Urology, University of Western Ontario, London, ON, Canada;

出版信息

Can Urol Assoc J. 2016 Mar-Apr;10(3-4):96-100. doi: 10.5489/cuaj.3237.

DOI:10.5489/cuaj.3237
PMID:27217854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4840009/
Abstract

INTRODUCTION

As early detection of hydronephrosis increases, we require better methods of distinguishing between pediatric patients who require pyeloplasty vs. those with transient obstruction. Gravity-assisted drainage (GAD) as part of a standardized diuretic renography protocol has been suggested as a simple and safe method to differentiate patients.

METHODS

Renal scans of 89 subjects with 121 hydronephrotic renal units between January 2004 and March 2007 were identified and analyzed.

RESULTS

Of all renal units, 65% showed obstruction. GAD maneuver resulted in significant residual tracer drainage in eight renal units, moderate drainage in 12 renal units, and some improvement in 40 units after the GAD maneuver. Of the eight renal units with significant residual tracer drainage, only two proceeded to pyeloplasty. After pyeloplasty, nine children had improved time to half maximum (T(1/2) Max) and 13 were unchanged.

CONCLUSIONS

Our study was limited due to its retrospective design and descriptive analyses, but includes a sufficient number of subjects to conclude that GAD as part of a diuretic renography protocol is an effective and simple technique that can help prevent unnecessary surgical procedures in pediatric patients.

摘要

引言

随着肾积水早期检测率的提高,我们需要更好的方法来区分需要肾盂成形术的儿科患者和有短暂梗阻的患者。重力辅助引流(GAD)作为标准化利尿肾图检查方案的一部分,已被认为是一种区分患者的简单安全的方法。

方法

对2004年1月至2007年3月期间89例有121个肾积水肾单位的受试者的肾脏扫描进行识别和分析。

结果

在所有肾单位中,65%显示有梗阻。GAD操作导致8个肾单位有大量放射性示踪剂残留引流,12个肾单位有中度引流,40个肾单位在GAD操作后有一定改善。在有大量放射性示踪剂残留引流的8个肾单位中,只有2个进行了肾盂成形术。肾盂成形术后,9名儿童的达峰时间减半(T(1/2) Max)有所改善,13名儿童则无变化。

结论

我们的研究由于其回顾性设计和描述性分析而受到限制,但纳入了足够数量的受试者以得出结论,即GAD作为利尿肾图检查方案的一部分是一种有效且简单的技术,可有助于防止儿科患者进行不必要的手术。

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Predicting the clinical outcome of antenatally detected unilateral pelviureteric junction stenosis.预测产前发现的单侧肾盂输尿管连接部狭窄的临床转归。
Urology. 2013 Sep;82(3):691-6. doi: 10.1016/j.urology.2013.03.041. Epub 2013 May 29.
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Critical analysis of outcome after open dismembered pyeloplasty in ectopic pelvic kidneys in a pediatric cohort.对小儿异位盆腔肾开放性离断肾盂成形术后结局的批判性分析。
Urology. 2012 Dec;80(6):1357-60. doi: 10.1016/j.urology.2012.07.057. Epub 2012 Oct 23.
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Guidelines for standard and diuretic renogram in children.儿童标准及利尿肾动态显像指南。
Eur J Nucl Med Mol Imaging. 2011 Jun;38(6):1175-88. doi: 10.1007/s00259-011-1811-3.
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Long-term follow-up and management of prenatally detected, isolated hydronephrosis.产前发现孤立性肾积水的长期随访和管理。
J Pediatr Surg. 2010 Aug;45(8):1701-6. doi: 10.1016/j.jpedsurg.2010.03.030.
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The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis.胎儿泌尿外科学会关于产前肾积水的评估和管理的共识声明。
J Pediatr Urol. 2010 Jun;6(3):212-31. doi: 10.1016/j.jpurol.2010.02.205. Epub 2010 Apr 15.
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Procedure guideline for diuretic renography in children 3.0.儿童利尿肾图操作指南3.0版
J Nucl Med Technol. 2008 Sep;36(3):162-8. doi: 10.2967/jnmt.108.056622.
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Scintigraphic renal function after unilateral pyeloplasty in children: a systematic review.儿童单侧肾盂成形术后的肾闪烁造影功能:一项系统评价
BJU Int. 2008 Sep;102(7):862-8. doi: 10.1111/j.1464-410X.2008.07597.x. Epub 2008 Mar 11.
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Management of neonatal hydronephrosis.新生儿肾积水的管理
Early Hum Dev. 2006 Jan;82(1):9-14. doi: 10.1016/j.earlhumdev.2005.11.004. Epub 2006 Jan 19.
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J Urol. 2003 May;169(5):1828-31. doi: 10.1097/01.ju.0000062640.46274.21.