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[急性肠梗阻揭示肠病相关T细胞淋巴瘤,一例报告]

[Acute intestinal obstruction revealing enteropathy associated t-cell lymphoma, about a case].

作者信息

Garba Abdoul Aziz, Adamou Harissou, Magagi Ibrahim Amadou, Brah Souleymane, Habou Oumarou

机构信息

Service de Médecine Interne et Générale, Hôpital National de Zinder, Niger.

Service de Chirurgie Générale et Digestive B, Hôpital National de Zinder, Niger.

出版信息

Pan Afr Med J. 2016 Feb 19;23:48. doi: 10.11604/pamj.2016.23.48.8909. eCollection 2016.

Abstract

Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency with acute intestinal obstruction. During the surgery, we found a tumor on the small intestine with mesenteric lymphadenopathy. Histology and immunohistochemistry of the specimen objectified a digestive T lymphoma CD3+ and immunological assessment of celiac disease was positive. The diagnosis of EATL was thus retained. Chemotherapy (CHOEP protocol) was established as well as gluten-free diet with a complete response to treatment. The EATL is a rare complication of CD that can be revealed by intestinal obstruction. The prognosis can be improved by early treatment involving surgery and chemotherapy. Its prevention requires early diagnosis of celiac and gluten-free diets.

摘要

肠病相关T细胞淋巴瘤(EATL)是乳糜泻(CD)的一种罕见并发症。我们报告一例因急性肠梗阻而发现的与CD相关的EATL病例。一名38岁有不孕史和慢性腹痛的北非女性因急性肠梗阻急诊入院。手术中,我们在小肠发现一个肿瘤,伴有肠系膜淋巴结病。标本的组织学和免疫组化证实为消化性T淋巴瘤CD3+,乳糜泻的免疫学评估呈阳性。因此确诊为EATL。制定了化疗方案(CHOEP方案)并采用无麸质饮食,治疗取得完全缓解。EATL是CD的一种罕见并发症,可由肠梗阻引发。早期进行手术和化疗等治疗可改善预后。其预防需要早期诊断乳糜泻并采用无麸质饮食。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcdf/4862778/548617c2f58e/PAMJ-23-48-g001.jpg

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