Eglite M E, Remez I M, Ustinenko A N, Ivanova I A, Shif B A
Gig Tr Prof Zabol. 1989(2):3-6.
It was established that allergic diseases of poultry farmers were characterized by the shifts in immunoregulation expressed in terms of the decrease of the number of T-lymphocyte-suppressors, precursors of effectory and immunoregulatory T-lymphocytes, reduction of functional actifity of T- and B-cells along with an increase in the content of B-lymphocytes with antibody-dependent killers' sensitization and suppression of nonspecific protective factors. The results suggested that the use of immunomodulatory drugs helped to improve clinicoimmunologic indicators.
已确定家禽养殖户的过敏性疾病具有免疫调节变化的特征,表现为T淋巴细胞抑制因子、效应性和免疫调节性T淋巴细胞前体数量减少,T细胞和B细胞功能活性降低,同时伴有抗体依赖性杀伤细胞致敏的B淋巴细胞含量增加以及非特异性保护因子受到抑制。结果表明,使用免疫调节药物有助于改善临床免疫指标。