Tudor A, Racoveanu C, Gheorghiu M, Georgescu M, Pecec C
Med Interne. 1985 Apr-Jun;23(2):129-34.
The present investigation was designed to the study of respiratory symptoms and immunologic changes in workers of a poultry farm, chronically exposed to various organic allergens (avian, fungi, etc.). The group studied included 202 exposed subjects (109 at the slaughter house, 93 on the farms) and 100 controls. Although the group was chiefly made up of young women, non-smokers, exposure to avian allergens increased the prevalence of respiratory symptoms. Thus, coughing and expectoration was noted in 8.2% of the workers in the slaughter house and 10.7% of those on the farms, wheezing being present especially in the latter (13.9%). An apparently obstructive pulmonary function was observed in 16.10% of the farm hands and 1% of controls. The study of humoral immunity suggested that the presence of precipitation antibodies (76% positive reactions in the farms, 63% in the slaughter house, 44% among the controls) indicated exposure to avian allergens rather than the clinical and radiologic presence of the disease.
本研究旨在调查长期接触各种有机过敏原（禽类、真菌等）的家禽养殖场工人的呼吸道症状和免疫变化。研究对象包括202名暴露组受试者（109名在屠宰场工作，93名在养殖场工作）和100名对照组。尽管该组主要由年轻女性、非吸烟者组成，但接触禽类过敏原仍增加了呼吸道症状的患病率。因此，屠宰场8.2%的工人和养殖场10.7%的工人出现咳嗽和咳痰症状，喘息症状尤其在后者中更为常见（13.9%）。农场工人中16.10%存在明显的阻塞性肺功能，而对照组这一比例为1%。体液免疫研究表明，沉淀抗体的存在（养殖场76%呈阳性反应，屠宰场63%，对照组44%）表明接触了禽类过敏原，而非疾病的临床和影像学表现。
