Kremer I, Svetliza E
Harefuah. 1989 Mar 1;116(5):252-4.
In recent years several investigators have reached the conclusion that the prognosis of melanoma of the iris is related to the cell type of the tumor. Overall mortality ranges from 3.0-3.6%, but there is no correlation between the clinical manifestation of the tumor, its microscopic appearance, or the results of angiography. The clinical behavior of histologically benign tumors may be malignant, with penetration through the trabeculum into the ciliary body and sclera, and there may even be recurrence following excision of the tumor. We present 2 women, 20 and 59 years old, respectively, with melanoma of the iris with malignant behavior. However, in 1 of them the microscopic picture was completely benign, although the tumor had penetrated into the angle of the anterior chamber and had caused severe secondary glaucoma.
近年来，一些研究人员得出结论，虹膜黑色素瘤的预后与肿瘤的细胞类型有关。总体死亡率在3.0%-3.6%之间，但肿瘤的临床表现、微观外观或血管造影结果之间没有相关性。组织学上良性的肿瘤临床行为可能是恶性的，可穿透小梁进入睫状体和巩膜，甚至在肿瘤切除后可能复发。我们报告2例分别为20岁和59岁的女性，患有具有恶性行为的虹膜黑色素瘤。然而，其中1例的微观图像完全良性，尽管肿瘤已侵入前房角并导致严重的继发性青光眼。
