Matson P L, Junk S M, Masters J R, Pryor J P, Yovich J L
PIVET Laboratory, Leederville, Perth, Western Australia.
Int J Androl. 1989 Apr;12(2):98-103. doi: 10.1111/j.1365-2605.1989.tb01291.x.
Seminal plasma samples from men undergoing vasovasostomy were analysed for antisperm antibodies using the indirect immunobead test. A pre-operative assessment showed antisperm antibodies of either IgA or IgG class to be present in 9/27 (33.3%) men. A significant increase (P less than 0.05) in the post-operative incidence of the antibodies was seen in the men who achieved patency (27/45, 60%) but not in those men for whom no sperm were seen in the ejaculate (4/10, 40%). After follow-up for a minimum of 1 year, conception rates for couples in which the male partner had achieved patency were similar in the groups with no antibodies detected post-operatively (12/18, 66.7%) or with IgA alone (2/3, 66.7%), but was reduced significantly in the presence of IgG (1/9, 11.1%; P less than 0.05) or IgA + IgG (3/15, 20.0%; P less than 0.01).
采用间接免疫珠试验对接受输精管吻合术男性的精浆样本进行抗精子抗体分析。术前评估显示，9/27（33.3%）的男性存在IgA或IgG类抗精子抗体。在输精管复通的男性中，术后抗体发生率显著增加（P<0.05）（27/45，60%），而在射精中未发现精子的男性中则未出现这种情况（4/10，40%）。在至少随访1年后，男性伴侣输精管复通的夫妇的受孕率在术后未检测到抗体的组（12/18，66.7%）或仅存在IgA的组（2/3，66.7%）中相似，但在存在IgG（1/9，11.1%；P<0.05）或IgA + IgG（3/15，20.0%；P<0.01）时显著降低。
