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输精管吻合术后未能受孕与精液中精子凝集素之间的关联。

Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen.

作者信息

Linnet L, Hjort T, Fogh-Andersen P

出版信息

Lancet. 1981 Jan 17;1(8212):117-9. doi: 10.1016/s0140-6736(81)90708-x.

DOI:10.1016/s0140-6736(81)90708-x
PMID:6109799
Abstract

Sperm agglutinins emerging from the reopened part of the vas deferens were found in the seminal fluid of 10 out of 29 men after vasovasostomy. There was a strong association between the presence of these antibodies and the failure to impregnate over a period of 14 to 33 months. Of 20 couples, 11 pregnancies resulted among the 13 women whose men had no sperm agglutinins in the seminal fluid, but only 1 among the 7 whose men had such antibodies, 2p = 0.0044. The presence of sperm agglutinins in the seminal fluid was always associated with their presence in the serum, usually in a higher titre. Preoperative serum levels thus are highly predictive of ability to impregnate after reversal of vasectomy.

摘要

在29名接受输精管吻合术的男性中,有10人的精液中发现了来自输精管重新开放部位的精子凝集素。这些抗体的存在与14至33个月内未能受孕之间存在强烈关联。在20对夫妇中,精液中无精子凝集素的13名男性的伴侣中有11人怀孕,但精液中有此类抗体的7名男性的伴侣中只有1人怀孕,P值为0.0044。精液中精子凝集素的存在总是与血清中精子凝集素的存在相关,通常血清中的滴度更高。因此,术前血清水平对输精管复通术后的受孕能力具有高度预测性。

相似文献

1
Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen.输精管吻合术后未能受孕与精液中精子凝集素之间的关联。
Lancet. 1981 Jan 17;1(8212):117-9. doi: 10.1016/s0140-6736(81)90708-x.
2
Immunologic considerations before and after vasovasostomy.输精管吻合术前后的免疫学考量
Fertil Steril. 1983 Oct;40(4):497-9. doi: 10.1016/s0015-0282(16)47362-0.
3
Fertilizing capacity and sperm antibodies in vasovasostomized men.输精管吻合术后男性的受精能力和精子抗体
Fertil Steril. 1983 Feb;39(2):197-203.
4
Reversal of vasectomy: the effects of sperm antibodies on subsequent fertility.输精管复通术:精子抗体对后续生育能力的影响。
Br J Urol. 1981 Dec;53(6):654-9. doi: 10.1111/j.1464-410x.1981.tb03284.x.
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Anti-sperm antibodies and semen profiles in re-anastomosed men.再吻合术后男性的抗精子抗体与精液分析
Reprod Fertil Dev. 1993;5(1):135-9. doi: 10.1071/rd9930135.
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Analysis of spermatozoa from the proximal vas deferens of vasectomized men.对输精管结扎男性近端输精管中的精子进行分析。
Int J Androl. 1994 Aug;17(4):181-5. doi: 10.1111/j.1365-2605.1994.tb01240.x.
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Microsurgical vasovasostomy: immunologic consequences and subsequent fertility.
Fertil Steril. 1981 Apr;35(4):447-50. doi: 10.1016/s0015-0282(16)45442-7.
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Low fertility rate in vasovasostomized males and its possible immunologic mechanism.输精管吻合术后男性的低生育率及其可能的免疫机制。
Int J Fertil. 1975;20(3):183-91.
9
Antisperm antibodies on the surface of spermatozoa before ejaculation from vasectomized men.输精管结扎术后男性射精前精子表面的抗精子抗体。
Reprod Contracept. 1997;8(1):27-31.
10
[Changes of free amino acids in seminal plasma with vasectomy and reanastomosis of the vas deferens (author's transl)].输精管结扎及输精管再吻合术后精浆中游离氨基酸的变化(作者译)
Nihon Funin Gakkai Zasshi. 1981 Apr;26(2):12-6.

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Vasectomy reversal: a clinical update.输精管复通术:临床最新进展
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An overview of the management of post-vasectomy pain syndrome.输精管结扎术后疼痛综合征的管理概述。
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Predictors of success in microsurgical correction of vasal and epididymal obstruction.输精管和附睾梗阻显微外科矫正成功的预测因素。
Curr Urol Rep. 2001 Dec;2(6):443-7. doi: 10.1007/s11934-001-0037-5.
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Analysis of the autoimmune epitopes on human testicular NASP using recombinant and synthetic peptides.使用重组肽和合成肽分析人睾丸核自体抗原精子蛋白(NASP)上的自身免疫表位。
Clin Exp Immunol. 2000 Aug;121(2):201-9. doi: 10.1046/j.1365-2249.2000.01303.x.
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The black mink (Mustela vison). A natural model of immunologic male infertility.黑貂(鼬属水貂)。免疫性男性不育的天然模型。
J Exp Med. 1981 Oct 1;154(4):1016-32. doi: 10.1084/jem.154.4.1016.
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Vasectomy reversal.输精管复通术
Ulster Med J. 1989 Oct;58(2):161-5.
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Vasectomy and the human testis.输精管切除术与人类睾丸
BMJ. 1990 Sep 29;301(6753):618-9. doi: 10.1136/bmj.301.6753.618.