最大灌注强度作为神经内血流超声标志物的效用。
Utility of maximum perfusion intensity as an ultrasonographic marker of intraneural blood flow.
作者信息
Borire Adeniyi A, Visser Leo H, Padua Luca, Colebatch James G, Huynh William, Simon Neil G, Kiernan Matthew C, Krishnan Arun V
机构信息
Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
St. Elisabeth Ziekenhuis, Tilburg, The Netherlands.
出版信息
Muscle Nerve. 2017 Jan;55(1):77-83. doi: 10.1002/mus.25200. Epub 2016 Nov 4.
UNLABELLED
We quantified intraneural blood flow (INBF) using perfusion measurement software (PixelFlux), and compared it with the qualitative method of counting blood vessels (vessel score) in a cohort of carpal tunnel syndrome (CTS) patients.
METHODS
Forty-seven patients (67 wrists) with a clinical and electrophysiological diagnosis of CTS, and 20 healthy controls (40 wrists) were enrolled. Median nerve ultrasound (US) was performed at the carpal tunnel inlet to measure the cross-sectional area (CSA) and vessel score. Power Doppler sonograms from nerves with detectable INBF were processed with PixelFlux to obtain the maximum perfusion intensity (MPI).
RESULTS
Forty-nine percent of CTS patients had detectable INBF compared with none in the control group (P < 0.0001). MPI correlated significantly with vessel score (r = 0.945, P < 0.0001), CSA (r = 0.613, P < 0.0001), and electrophysiological severity (r = 0.440, P < 0.0001). MPI had higher intra- or interobserver reliability compared with vessel score (0.95 vs. 0.47).
CONCLUSION
MPI is a better method for quantification of INBF. Muscle Nerve, 2016 Muscle Nerve 55: 77-83, 2017.
未标注
我们使用灌注测量软件（PixelFlux）对神经内血流（INBF）进行定量，并将其与一组腕管综合征（CTS）患者中计数血管的定性方法（血管评分）进行比较。
方法
纳入47例临床和电生理诊断为CTS的患者（67只手腕）以及20例健康对照者（40只手腕）。在腕管入口处进行正中神经超声（US）检查，以测量横截面积（CSA）和血管评分。对可检测到INBF的神经的功率多谱勒超声图用PixelFlux进行处理，以获得最大灌注强度（MPI）。
结果
49%的CTS患者可检测到INBF，而对照组无一例可检测到（P < 0.0001）。MPI与血管评分（r = 0.945，P < 0.0001）、CSA（r = 0.613，P < 0.0001）以及电生理严重程度（r = 0.440，P < 0.0001）显著相关。与血管评分相比，MPI具有更高的观察者内或观察者间可靠性（0.9 vs. 0.47）。
结论
MPI是定量INBF的更好方法。《肌肉与神经》，2016年。《肌肉与神经》55: 77 - 83，2017年。
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