Pugmire Brian S, Towbin Alexander J
Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC-5031, Cincinnati, OH, 45255, USA.
Pediatr Radiol. 2016 May;46(6):764-77. doi: 10.1007/s00247-016-3612-0. Epub 2016 May 26.
Although primary hepatic neoplasms are less common than other intra-abdominal tumors in children, these neoplasms are a significant source of morbidity and mortality in the pediatric population. MRI is increasingly relied upon in the diagnostic evaluation of these lesions, both before and after treatment, and familiarity with the MRI findings associated with these neoplasms is a must for pediatric radiologists. Advances in MRI technology, particularly the advent of hepatocyte-specific gadolinium-based MRI contrast agents, have allowed for accurate characterization of several types of hepatic neoplasms on the basis of imaging appearance. In this review, we provide an overview of the approach to imaging hepatic neoplasms in children using MRI, including a sample imaging protocol. We also discuss the relevant clinical features and MRI findings of the most clinically relevant entities, including their appearance on post-contrast imaging using hepatocyte-specific gadolinium-based MRI contrast agents.
虽然原发性肝脏肿瘤在儿童中比其他腹部肿瘤少见,但这些肿瘤是儿科人群发病和死亡的重要原因。在这些病变的诊断评估中,无论是治疗前还是治疗后,MRI的应用越来越广泛,儿科放射科医生必须熟悉与这些肿瘤相关的MRI表现。MRI技术的进步,特别是基于钆的肝细胞特异性MRI造影剂的出现,使得根据影像学表现对几种类型的肝脏肿瘤进行准确的特征性诊断成为可能。在本综述中,我们概述了使用MRI对儿童肝脏肿瘤进行成像的方法,包括一个示例成像方案。我们还讨论了最具临床相关性的实体的相关临床特征和MRI表现,包括它们在使用基于钆的肝细胞特异性MRI造影剂的增强成像上的表现。