Axelsson K F, Jacobsson R, Lund D, Lorentzon M
Department of Orthopaedic Surgery, Skaraborg Hospital, Skövde, Sweden.
Geriatric Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Building K, 6th Floor, Mölndal, 431 80, Sweden.
Osteoporos Int. 2016 Nov;27(11):3165-3175. doi: 10.1007/s00198-016-3643-2. Epub 2016 May 26.
The purpose of this study was to investigate if a 2-year intervention with a minimal resource fracture liaison service (FLS) was associated with increased investigation and medical treatment and if treatment was related to reduced re-fracture risk.
The FLS started in 2013 using existing secretaries (without an FLS coordinator) at the emergency department and orthopaedic wards to identify risk patients. All patients older than 50 years of age with a fractured hip, vertebra, shoulder, wrist or pelvis were followed during 2013-2014 (n = 2713) and compared with their historic counterparts in 2011-2012 (n = 2616) at the same hospital. Re-fractures were X-ray verified. A time-dependent adjusted (for age, sex, previous fracture, index fracture type, prevalent treatment, comorbidity and secondary osteoporosis) Cox model was used.
The minimal resource FLS increased the proportion of DXA-investigated patients after fracture from 7.6 to 39.6 % (p < 0.001) and the treatment rate after fracture from 12.6 to 31.8 %, which is well in line with FLS types using the conventional coordinator model. Treated patients had a 51 % lower risk of any re-fracture than untreated patients (HR 0.49, 95 % CI 0.37-0.65 p < 0.001).
We found that our minimal resource FLS was effective in increasing investigation and treatment, in line with conventional coordinator-based services, and that treated patients had a 51 % reduced risk of new fractures, indicating that also non-coordinator based fracture liaison services can improve secondary prevention of fractures.
本研究旨在调查一项为期两年、资源极少的骨折联络服务(FLS)干预措施是否与检查和医疗治疗的增加相关,以及治疗是否与降低再骨折风险有关。
FLS于2013年启动,利用急诊科和骨科病房现有的秘书(无FLS协调员)来识别风险患者。对2013年至2014年期间所有年龄超过50岁、髋部、脊椎、肩部、腕部或骨盆骨折的患者(n = 2713)进行随访,并与同一家医院2011年至2012年的历史对照患者(n = 2616)进行比较。再骨折经X线证实。使用了一个时间依赖性调整(针对年龄、性别、既往骨折、索引骨折类型、现有治疗、合并症和继发性骨质疏松症)的Cox模型。
资源极少的FLS使骨折后接受双能X线吸收法(DXA)检查的患者比例从7.6%提高到39.6%(p < 0.001),骨折后的治疗率从12.6%提高到31.8%,这与使用传统协调员模式的FLS类型相符。接受治疗的患者发生任何再骨折的风险比未接受治疗的患者低51%(风险比0.49,95%置信区间0.37 - 0.65,p < 0.001)。
我们发现,我们资源极少的FLS在增加检查和治疗方面是有效的,与基于传统协调员的服务一致,并且接受治疗的患者发生新骨折的风险降低了51%,这表明基于非协调员的骨折联络服务也可以改善骨折的二级预防。