骨折联络服务在髋部骨折患者中的有效性：一项随机对照试验的系统评价和荟萃分析。

The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials.

作者信息

Yan Chengli, Chen Yuyu, Cao Jia, Fang Kai, Shao Lifang, Luo Yaping, Yang Lili

机构信息

Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.

Nursing Department, Dazhou Central Hospital, Sichuan, China.

出版信息

Heliyon. 2023 Oct 10;9(10):e20838. doi: 10.1016/j.heliyon.2023.e20838. eCollection 2023 Oct.

DOI:10.1016/j.heliyon.2023.e20838

PMID:37867909

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10585289/

Abstract

BACKGROUND

In recent years, fracture liaison services (FLS) have been applied for hip fractures; however, their effectiveness remains uncertain.

OBJECTIVE

To evaluate the effectiveness of FLS in patients with hip fractures.

DESIGN

A systematic review and meta-analysis of randomized controlled trials.

DATA SOURCES

Embase, PubMed, Cochrane Library, Ebsco, Ovid, Web of Science, Medline, CNKI, Wangfang, and Vip were searched from their date of inception to March 2023. Two researchers screened the literature based on the inclusion and exclusion criteria, evaluated the quality, extracted data, and conducted a meta-analysis using ReviewManager 5.4.

RESULTS

After screening, 12 randomised controlled trials (RCT) including 2136 patients were used in the meta-analysis. The primary outcomes were hip function rate of recurrent fracture, medication adherence, and degree of weakness. FLS improved hip function in patients with hip fractures [MD = 9.37, 95 % CI (7.69, 11.06), P < 0.0001], P < 0.0001], medication adherence [OR = 10.59, 95 % CI (1.64, 68.41), P＜0.0001], degree of weakness [MD = -1.45, 95%CI (-1.68，-1.23), P＜0.0001], and reduced the rate of recurrent fractures [OR = 0.60, 95 % CI (0.44, 0.82).

CONCLUSION

Implementation of the FLS management model was beneficial for patients with hip fractures. It can positively impact the prognosis of patients with hip fractures by improving hip function, reducing the rate of recurrent fractures, and improving medication adherence and degree of weakness.

摘要

背景

近年来，骨折联络服务（FLS）已应用于髋部骨折；然而，其有效性仍不确定。

目的

评估骨折联络服务对髋部骨折患者的有效性。

设计

对随机对照试验进行系统评价和荟萃分析。

数据来源

检索了Embase、PubMed、Cochrane图书馆、Ebsco、Ovid、Web of Science、Medline、知网、万方和维普，检索时间从各数据库创建之日至2023年3月。两名研究人员根据纳入和排除标准筛选文献，评估质量，提取数据，并使用ReviewManager 5.4进行荟萃分析。

结果

筛选后，12项随机对照试验（RCT）共2136例患者纳入荟萃分析。主要结局指标为髋部功能、再骨折发生率、药物依从性和虚弱程度。骨折联络服务改善了髋部骨折患者的髋部功能[MD = 9.37，95%CI（7.69，11.06），P < 0.0001]、药物依从性[OR = 10.59，95%CI（1.64，68.41），P＜0.0001]、虚弱程度[MD = -1.45，95%CI（-1.68，-1.23），P＜0.0001]，并降低了再骨折发生率[OR = 0.60，95%CI（0.44，0.82）]。