From the Department of Medicine, Section of Vascular Medicine, Cardiovascular Division, Vanderbilt University School of Medicine, Nashville, TN (J.A.B.); and Department of Medicine, Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH (M.A.C.).
Circ Res. 2016 May 27;118(11):1771-85. doi: 10.1161/CIRCRESAHA.115.306884.
Over the last several decades, the global incidence and prevalence of diabetes mellitus has increased significantly. The raised incidence rate is projected to continue as greater numbers of persons adopt a Western lifestyle and diet. Patients with diabetes mellitus are at heightened risk of both adverse microvascular and cardiovascular events. Moreover, once cardiovascular disease develops, diabetes mellitus exacerbates progression and worsens outcomes. The medical management of patients with diabetes mellitus mandates comprehensive risk factor modification and antiplatelet therapy. Recent clinical trials of new medical therapies continue to inform the care of patients with diabetes mellitus to reduce both cardiovascular morbidity and mortality.
在过去几十年中，全球糖尿病的发病率和流行率显著上升。随着更多人采用西方生活方式和饮食，预计发病率还会继续上升。糖尿病患者发生不良微血管和心血管事件的风险增加。此外，一旦发生心血管疾病，糖尿病会使病情恶化，预后变差。糖尿病患者的医学管理需要全面的危险因素调整和抗血小板治疗。最近关于新的医学治疗的临床试验继续为糖尿病患者的治疗提供信息，以降低心血管发病率和死亡率。
