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使用单分子实时测序技术测定伪狂犬病病毒参考毒株NIA3的全基因组序列

Complete Genome Sequence of Pseudorabies Virus Reference Strain NIA3 Using Single-Molecule Real-Time Sequencing.

作者信息

Mathijs Elisabeth, Vandenbussche Frank, Verpoest Sara, De Regge Nick, Van Borm Steven

机构信息

Molecular Platform, Veterinary and Agrochemical Research Centre, Ukkel, Belgium

Molecular Platform, Veterinary and Agrochemical Research Centre, Ukkel, Belgium.

出版信息

Genome Announc. 2016 May 26;4(3):e00440-16. doi: 10.1128/genomeA.00440-16.

Abstract

Pseudorabies virus (PRV) is the causative agent of Aujeszky's disease in pigs. PRV strains are also used as model organisms for the study of alphaherpesvirus biology or for neuronal pathway studies. We present here the complete genome of the virulent wild-type PRV reference strain NIA3, determined by single-molecule real-time sequencing.

摘要

伪狂犬病病毒(PRV)是猪奥耶斯基氏病的病原体。PRV毒株也被用作研究α疱疹病毒生物学或神经元通路的模式生物。我们在此展示了通过单分子实时测序确定的强毒野生型PRV参考毒株NIA3的完整基因组。

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