Zhou Dong, Deng Xu-Feng, Liu Quan-Xing, Chen Qian, Min Jia-Xin, Dai Ji-Gang
Department of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China.
Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing, 400037, China.
J Cardiothorac Surg. 2016 May 27;11(1):88. doi: 10.1186/s13019-016-0484-1.
In this meta-analysis, we conducted a pooled analysis of clinical studies comparing the efficacy of single chest tube versus double chest tube after a lobectomy.
According to the recommendations of the Cochrane Collaboration, we established a rigorous study protocol. We performed a systematic electronic search of the PubMed, Embase, Cochrane Library and Web of Science databases to identify articles to include in our meta-analysis. A literature search was performed using relevant keywords. A meta-analysis was performed using RevMan© software.
Five studies, published between 2003 and 2014, including 630 patients (314 patients with a single chest tube and 316 patients with a double chest tube), met the selection criteria. From the available data, the patients using a single tube demonstrated significantly decreased postoperative pain [weighted mean difference [WMD] -0.60; 95 % confidence intervals [CIs] -0.68-- 0.52; P < 0.00001], duration of drainage [WMD -0.70; 95 % CIs -0.90-- 0.49; P < 0.00001] and hospital stay [WMD -0.51; 95 % CIs -0.91-- 0.12; P = 0.01] compared to patients using a double tube after a pulmonary lobectomy. However, there were no significant differences in postoperative complications [OR 0.91; 95 % CIs 0.57-1.44; P = 0.67] and re-drainage rates [OR 0.81; 95 % CIs 0.42-1.58; P = 0.54].
Our results showed that a single-drain method is effective, reducing postoperative pain, hospitalization times and duration of drainage in patients who undergo a lobectomy. Moreover, the single-drain method does not increase the occurrence of postoperative complications and re-drainage rates.
在这项荟萃分析中,我们对比较肺叶切除术后单根胸管与双根胸管疗效的临床研究进行了汇总分析。
根据Cochrane协作网的建议,我们制定了严格的研究方案。我们对PubMed、Embase、Cochrane图书馆和科学网数据库进行了系统的电子检索,以确定纳入我们荟萃分析的文章。使用相关关键词进行文献检索。使用RevMan©软件进行荟萃分析。
2003年至2014年间发表的5项研究,共630例患者(314例使用单根胸管,316例使用双根胸管)符合入选标准。根据现有数据,与肺叶切除术后使用双根胸管的患者相比,使用单根胸管的患者术后疼痛明显减轻[加权平均差[WMD]-0.60;95%置信区间[CI]-0.68--0.52;P<0.00001],引流时间[WMD -0.70;95% CI -0.90--0.49;P<0.00001]和住院时间[WMD -0.51;95% CI -0.91--0.12;P = 0.01]。然而,术后并发症[比值比[OR]0.91;95% CI 0.57 - 1.44;P = 0.67]和再次引流率[OR 0.81;95% CI 0.42 - 1.58;P = 0.54]无显著差异。
我们的结果表明,单根引流法是有效的,可减轻肺叶切除患者的术后疼痛、缩短住院时间和引流时间。此外,单根引流法不会增加术后并发症的发生率和再次引流率。