Mio Y, Sugimoto T, Iwabe T, Sekijima A, Oonohara Y, Tanikawa M, Terado H, Toda T, Harada T, Kikukawa A
Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yanago.
Nihon Sanka Fujinka Gakkai Zasshi. 1989 Feb;41(2):129-36.
In order to evaluate the effectiveness and safety of ultrasonic oocyte collection for IVF-ET, a comparative study was performed on the results of IVF-ET by the transabdominal and transvaginal methods in 145 cycles of 51 patients. The oocyte collection rate for the transvaginal method was significantly higher than that for the transabdominal method (77.1% vs. 68.7% per follicle, p less than 0.01). The majority of the oocytes were collected in three follicular flushings. The fertilization rate for oocytes collected by the transabdominal method was significantly higher than that for those collected by the transvaginal method in cases of tubal damage and endometriosis (81.1% vs. 65.6% per oocyte, p less than 0.01). There was no significant difference between the signs of complications seen with the two methods. Six successful pregnancies were obtained by IVF-ET in our hospital (4 cases by the transabdominal method, and 2 cases by the transvaginal method). Two of these cases have already delivered full term healthy male infants. In conclusion, these results indicate that ultrasonic oocyte collection has been established as the most effective method for IVF-ET by means of either the transabdominal or the transvaginal methods.
为评估超声取卵用于体外受精-胚胎移植(IVF-ET)的有效性和安全性,对51例患者145个周期经腹和经阴道途径IVF-ET的结果进行了一项对比研究。经阴道取卵法的取卵率显著高于经腹取卵法(每个卵泡分别为77.1%和68.7%,p<0.01)。大部分卵母细胞通过三次卵泡冲洗获取。在输卵管损伤和子宫内膜异位症患者中,经腹取卵法获取的卵母细胞受精率显著高于经阴道取卵法(每个卵母细胞分别为81.1%和65.6%,p<0.01)。两种方法的并发症体征无显著差异。我院通过IVF-ET获得了6例成功妊娠(经腹取卵法4例,经阴道取卵法2例)。其中2例已足月分娩健康男婴。总之,这些结果表明,超声取卵已成为经腹或经阴道途径IVF-ET最有效的方法。