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西澳大利亚的体外受精。一项可行的服务项目。

In-vitro fertilization in Western Australia. A viable service programme.

作者信息

Yovich J L, Stanger J D, Tuvik A I, Yovich J M

出版信息

Med J Aust. 1984 May 26;140(11):645-9.

PMID:6232444
Abstract

A service programme of in-vitro fertilization ( IVF ) and embryo transfer (ET) has been established in a small unit in Western Australia after a successful pilot study which was undertaken in 1981. The key features of the programme include simplified monitoring of the follicular phase of stimulated cycles; oocyte retrieval and ET are both undertaken during routine daytime work schedules. The results of the first eight months of the programme are presented, during which 13 further pregnancies were generated and 10 healthy infants were delivered (seven boys and three girls). In the last session in which 49 patients took part a mean of 2.3 mature preovulatory oocytes were collected by means of a double-lumen aspiration/flushing needle from 98% of 48 patients who reached the laparoscopy stage. Ninety-four per cent of 48 patients proceeded to embryo transfer by means of a double-catheter technique; the pregnancy rate was 20.8% per laparoscopy or 22.7% per embryo transfer.

摘要

在西澳大利亚的一个小单位,继1981年成功开展一项试点研究之后,建立了一项体外受精(IVF)和胚胎移植(ET)服务计划。该计划的关键特征包括简化对刺激周期卵泡期的监测;卵母细胞采集和胚胎移植均在常规日间工作日程中进行。本文展示了该计划前八个月的结果,在此期间又有13例妊娠并分娩了10名健康婴儿(7名男孩和3名女孩)。在最后一次有49名患者参与的环节中,通过双腔抽吸/冲洗针,从48名进入腹腔镜检查阶段患者中的98%采集到了平均2.3个成熟的排卵前卵母细胞。48名患者中的94%通过双导管技术进行了胚胎移植;腹腔镜检查的妊娠率为20.8%,每次胚胎移植的妊娠率为22.7%。

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