Allen Caitlin, Evans Ginger, Sutton Eliza L
Department of Medicine, University of Wisconsin School of Medicine and Public Health, 5120 MFCB, 1685 Highland Avenue, Madison, WI 53705, USA.
Department of Medicine, VA Puget Sound Health Care System, University of Washington, 1660 South Columbian Way, S-123-PCC, Seattle, WA 98108, USA.
Med Clin North Am. 2016 Jul;100(4):763-89. doi: 10.1016/j.mcna.2016.03.008.
Female hormones play a significant role in the etiology and treatment of many women's health conditions. This article focuses on the common uses of hormonal therapy. When prescribing estrogen-containing regimens throughout the span of a woman's life, the risks are similar (ie, cardiovascular risk and venous thromboembolism), but the degree of risk varies significantly depending on a woman's particular set of risk factors and the details of the hormone regimen. In addition to estrogens and progestogens, this article also touches on the use of selective steroid receptor modulators in emergency contraception and in treatment of menopause symptoms.
女性激素在许多女性健康状况的病因和治疗中起着重要作用。本文重点关注激素疗法的常见用途。在女性一生中开具含雌激素方案时,风险相似(即心血管风险和静脉血栓栓塞),但风险程度因女性特定的风险因素组合和激素方案的细节而有显著差异。除了雌激素和孕激素外,本文还涉及选择性类固醇受体调节剂在紧急避孕和更年期症状治疗中的应用。