细胞间线粒体转移：细胞间的生物能量串扰
Intercellular mitochondrial transfer: bioenergetic crosstalk between cells.
作者信息
Sinha Pratik, Islam Mohammad N, Bhattacharya Sunita, Bhattacharya Jahar
机构信息
Department of Medicine, Columbia University, New York, NY 10032, USA.
Department of Medicine, Columbia University, New York, NY 10032, USA; Department of Pediatrics, Columbia University, New York, NY 10032, USA.
出版信息
Curr Opin Genet Dev. 2016 Jun;38:97-101. doi: 10.1016/j.gde.2016.05.002. Epub 2016 May 25.
Abstract
Mitochondrial transfer from donor cells to cells of injured tissues is a promising cell-based therapy for effectively bringing about recovery of tissue bioenergetics. Here, we review recent studies on intercellular mitochondrial transfer in organs and cells. We also review studies that shed light on our current understanding of the known mechanisms and conditions that lead to intercellular mitochondrial transfer.
摘要
从供体细胞向受损组织细胞进行线粒体转移，是一种前景广阔的基于细胞的疗法，能够有效促进组织生物能量学的恢复。在此，我们综述了近期关于器官和细胞间线粒体转移的研究。我们还综述了一些研究，这些研究有助于我们目前对导致细胞间线粒体转移的已知机制和条件的理解。
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