Holt Lynda
Emerg Nurse. 2002 May 1;10(2):7. doi: 10.7748/en.10.2.7.s11.
Burn studies in humans and animals that have tested large doses of heparin topically and parenterally have produced significant therapeutic results. Relieved pain, enhanced healing, and smooth skin were findings. Fewer resuscitation fluids, fewer lung and intestinal complications, and fewer infections were reported. These burn studies revealed that heparin had anti-inflammatory, neoangiogenic, collagen-restoring, and epithelialising effects in addition to its anti-coagulating effects.
在人体和动物身上进行的烧伤研究中，对大剂量肝素进行局部和胃肠外给药测试，已产生显著的治疗效果。研究发现，疼痛得到缓解、愈合加快且皮肤恢复光滑。报告显示复苏液体用量减少、肺部和肠道并发症减少、感染减少。这些烧伤研究表明，肝素除了具有抗凝血作用外，还具有抗炎、促进新血管生成、恢复胶原蛋白以及促进上皮形成的作用。
