Saliba M J
Acta Chir Plast. 1997;39(1):13-6.
Burn care has been mostly surgical, difficult, and expensive. The use of adequately large doses of heparin administered both parenterally and topically improved burn treatment and quality of life (1-20). Burn pain was relieved. Patients were not toxic. Tissue swelling, resuscitation fluids, and healing time were reduced. Pulmonary and intestinal pathology were notably absent. The new skin was smooth, comfortable, and contracture free. More than anticoagulating effect were seen. Antiinflammatory effects, active at acidic phs but not at alkaline phs, stopped burn pain inflammation, and extension. Neoangiogenic effects revascularized ischemic tissue. Reepithelializing effects were evident. Nonburn and recent burn studies confirmed that heparin had these strong properties and effects (7-13, 21-34). Medical and surgical procedures were reduced. Burn care became simpler and easier. Precautions to prevent bleeding were used. Current use of heparin is limited. Wider use is warranted.
烧伤护理大多涉及外科手术，难度大且费用高。经肠胃外和局部给予足够大剂量的肝素改善了烧伤治疗及生活质量（1 - 20）。烧伤疼痛得到缓解。患者未出现中毒现象。组织肿胀、复苏液用量及愈合时间均有所减少。肺部和肠道病变显著减轻。新生皮肤光滑、舒适且无挛缩。观察到的作用不止于抗凝效果。抗炎作用在酸性pH值时有效，在碱性pH值时无效，可阻止烧伤疼痛炎症及扩散。新生血管生成作用使缺血组织重新血管化。上皮再生作用明显。非烧伤和近期烧伤研究证实肝素具有这些强大特性和作用（7 - 13，21 - 34）。医疗和外科手术减少。烧伤护理变得更简单容易。采取了预防出血的措施。肝素目前的应用有限。有必要更广泛地使用。
