Lemaire X, Bonnet E, Castan B, Forestier E, Lescure F-X, Roblot F, Pulcini C
Service maladies infectieuses, CH de Douai, 59500 Douai, France.
Unité mobile d'infectiologie, hôpital J.-Ducuing, 15, rue Varsovie, 31300 Toulouse, France.
Med Mal Infect. 2016 Oct;46(7):355-359. doi: 10.1016/j.medmal.2016.04.005. Epub 2016 May 26.
We aimed to assess medical practices of French infectious disease specialists or any other relevant physicians related to the management of non-necrotizing cellulitis (NNC).
We sent an online questionnaire to members of the French Infectious Diseases Society (SPILF) mailing list in September 2015.
A total of 108 specialists took part in the survey and 10% (11/107) declared to always admit NNC patients to hospital. As for the others, 18% declared to admit patients in more than 80% of cases, 49% in 50-80% of cases, 26% in 20-50% of cases, and 7% in less than 20% of cases. The most frequent criteria for hospital admission were severe sepsis/septic shock (99%), poor social conditions (99%), rapid extension of skin lesions (93%), high level of pain (86%), and failure of first-line antibiotic therapy (84%). Participants mentioned similar criteria for reasons to initiate the intravenous (IV) antibiotic therapy. Fifty-three percent of respondents declared initiating antibiotic therapy using the IV route in more than 80% of cases. Physicians declared that the usual antibiotic therapy duration were <7 days (6%), 8-10 days (57%), 11-14 days (34%), and >15 days (3%).
Criteria for hospital admission and use of the IV route for antibiotic therapy as well as optimal treatment duration in patients presenting with NNC need to be detailed in guidelines and evaluated in prospective studies.
我们旨在评估法国传染病专家或其他相关医生针对非坏死性蜂窝织炎(NNC)管理的医疗实践。
2015年9月,我们向法国传染病学会(SPILF)邮件列表中的成员发送了一份在线调查问卷。
共有108名专家参与了调查,10%(11/107)表示总是将NNC患者收住入院。至于其他专家,18%表示在超过80%的病例中收住患者,49%在50%-80%的病例中收住,26%在20%-50%的病例中收住,7%在不到20%的病例中收住。最常见的住院标准是严重脓毒症/脓毒性休克(99%)、社会条件差(99%)、皮肤病变迅速扩展(93%)、疼痛程度高(86%)以及一线抗生素治疗失败(84%)。参与者提到了启动静脉(IV)抗生素治疗的类似标准。53%的受访者表示在超过80%的病例中采用IV途径启动抗生素治疗。医生表示通常的抗生素治疗持续时间为<7天(6%)、8-10天(57%)、11-14天(34%)和>15天(3%)。
对于NNC患者,住院标准、抗生素治疗IV途径的使用以及最佳治疗持续时间需要在指南中详细说明,并在前瞻性研究中进行评估。