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舌背外胚间叶性软骨黏液样瘤伴言语障碍

Ectomesenchymal Chondromyxoid Tumour of the Dorsal Tongue Presenting with Impaired Speech.

作者信息

Schep Laura A, Bullock Martin J, Taylor S Mark

机构信息

Faculty of Medicine, Dalhousie University, 6299 South Street, Halifax, NS, Canada B3H 4R2.

Faculty of Medicine, Dalhousie University, 6299 South Street, Halifax, NS, Canada B3H 4R2; Division of Pathology, Dalhousie University, 6299 South Street, Halifax, NS, Canada B3H 4R2.

出版信息

Case Rep Otolaryngol. 2016;2016:7342910. doi: 10.1155/2016/7342910. Epub 2016 Apr 28.

Abstract

Ectomesenchymal chondromyxoid tumours (ECTs) are rare mesenchymal soft tissue neoplasms that typically present as a slow-growing asymptomatic mass on the anterior dorsum of the tongue. Our patient presented with impaired speech articulation and pain associated with upper respiratory tract infections when the lesion on his dorsal tongue would swell, and he would accidentally bite down on it. Microscopically, ECTs appear as unencapsulated, well-circumscribed proliferations of uniform round to fusiform cells embedded within chondromyxoid matrices. Most cases of ECT have been detected in the third to the sixth decades of life, with no sex preference. ECT may cause a range of symptoms that negatively impact patients' quality of life, including pain, dysphagia, odynophagia, bleeding, and, in the case of our patient, impairment of speech. We provide a unique preoperative clinical photograph and case description that should help readers in recognizing this neoplasm. Considering the rarity of ECT presenting clinically as well as in the literature, we believe this report will add to our growing understanding of ECT and its management. We report a case of ECT presenting on the anterior dorsal tongue that was successfully surgically resected under local anesthesia with clear margins, accompanied by a review of the pertinent literature.

摘要

外胚间叶性软骨黏液样肿瘤(ECTs)是一种罕见的间叶性软组织肿瘤,通常表现为舌背前部缓慢生长的无症状肿块。我们的患者在舌背病变肿胀时出现言语清晰度受损,并伴有上呼吸道感染相关的疼痛,且他会不小心咬到病变部位。在显微镜下,ECTs表现为无包膜、边界清楚的增殖,由均匀的圆形至梭形细胞包埋于软骨黏液样基质中。ECT的大多数病例在30至60岁被发现,无性别差异。ECT可能导致一系列对患者生活质量产生负面影响的症状,包括疼痛、吞咽困难、吞咽痛、出血,就我们的患者而言,还包括言语障碍。我们提供了一张独特的术前临床照片和病例描述,这应有助于读者识别这种肿瘤。鉴于ECT在临床和文献中均很罕见,我们相信本报告将增进我们对ECT及其治疗的认识。我们报告一例发生于舌背前部的ECT,在局部麻醉下成功进行了手术切除,切缘清晰,并对相关文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e10b/4864532/0958f473ddcc/CRIOT2016-7342910.001.jpg

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