类风湿关节炎患者听力损失的患病率

Prevalence Rate of Hearing Loss in Patients with Rheumatoid Arthritis.

作者信息

Almasi Simin, Mehrabian Fatemeh, Rahbar Nariman, Delarestaghi Mojtaba Maleki

机构信息

Department of Rheumatology, Rheumatology Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

Department of Rheumatology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Adv Biomed Res. 2023 Mar 28;12:80. doi: 10.4103/abr.abr_118_21. eCollection 2023.

DOI:10.4103/abr.abr_118_21

PMID:37200746

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10186036/

Abstract

BACKGROUND

Rheumatoid arthritis (RA) is a common chronic inflammatory disorder that can be associated with some hearing impairments. Hence, we aimed to evaluate the prevalence rate of hearing loss (HL) in RA patients.

MATERIALS AND METHODS

This study included 130 participants from February 2019 to March 2020 including 100 RA patients (78 females and 22 males) as RA group and 30 healthy cases (16 females and 14 males) as control group. All patients underwent pure tone audiometry, speech audiometry, tympanometry, acoustic reflex, and tone decay test by single operator and device. The rate of HL and contributing factors were then determined.

RESULTS

The mean age of RA group was 53.95 ± 7.6 years, and the mean duration of disease was 12.74 years. Rheumatoid factor was positive in 54% of patients, and the frequency rates of diabetes, chronic kidney disease, hypertension, and dyslipidemia among RA patients were 14%, 1%, 26%, and 19%, respectively. These values among RA patients with HL were 18%, 1.7%, 34%, and 27.5%, respectively. HL in RA patients was related to dyslipidemia ( = 0.011) and age ( = 0.0001). Frequency rate of conductive HL in left and right ears was 2% and 5%, respectively, and these rates for sensorineural hearing loss (SNHL) were 55% and 61%, respectively. In addition, the percent of HL in low, mid, and high frequency ranges was 18%, 19%, and 57%, respectively.

CONCLUSIONS

The findings of the present research demonstrate that HL especially with SNHL and high-frequency types is common among RA patients.

摘要

背景

类风湿性关节炎（RA）是一种常见的慢性炎症性疾病，可能与一些听力障碍有关。因此，我们旨在评估类风湿性关节炎患者听力损失（HL）的患病率。

材料与方法

本研究纳入了2019年2月至2020年3月的130名参与者，其中100名类风湿性关节炎患者（78名女性和22名男性）作为类风湿性关节炎组，30名健康受试者（16名女性和14名男性）作为对照组。所有患者均由一名操作人员使用同一设备进行纯音听力测定、言语听力测定、鼓室图、声反射和音衰试验。然后确定听力损失率及其相关因素。

结果

类风湿性关节炎组的平均年龄为53.95±7.6岁，平均病程为12.74年。54%的患者类风湿因子呈阳性，类风湿性关节炎患者中糖尿病、慢性肾病、高血压和血脂异常的发生率分别为14%、1%、26%和19%。在有听力损失的类风湿性关节炎患者中，这些数值分别为18%、1.7%、34%和27.5%。类风湿性关节炎患者的听力损失与血脂异常（P = 0.011）和年龄（P = 0.0001）有关。左耳和右耳传导性听力损失的发生率分别为2%和5%，感音神经性听力损失（SNHL）的发生率分别为55%和61%。此外，低频、中频和高频范围内听力损失的百分比分别为18%、19%和57%。